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Recombinant Human Protocadherin Fat 2 (FAT2), partial

Recombinant Human Protocadherin Fat 2 (FAT2), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

FAT2

Purity

>85% (SDS-PAGE)

Target Names

FAT2

Uniprot NO.

Q9NYQ8

Species

Homo sapiens (Human)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Involved in the regulation of cell migration. May be involved in mediating the organization of the parallel fibers of granule cells during cerebellar development.

Gene References into Functions

DeltaNp63alpha (TP63) is co-expressed with FAT2 and Slug in patient tumors and the elevated expression of DeltaNp63alpha, FAT2 and Slug correlated with poor patient outcome. PMID:27081041
Human Fat2 is localized at immature adherens junctions in epidermal keratinocytes. PMID:17900869

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Subcellular Location

Cell membrane; Single-pass type I membrane protein. Cell junction. Golgi apparatus, trans-Golgi network.

Tissue Specificity

Expressed in epidermal keratinocytes, infant brain, cerebellum, and also in a variety of tumors, such as pancreatic cancer, diffuse type gastric cancer, ovarian cancer, esophageal cancer, skin squamous cell carcinoma, head and neck cancer. Not expressed i

Database Links

HGNC: 3596

UNIGENE: Hs.591255

KEGG: hsa:2196

STRING: 9606.ENSP00000261800

OMIM: 604269

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