Recombinant Human Probable G-protein coupled receptor 133 (GPR133), partial

Product Details

Abbreviation
GPR133
Purity
>85% (SDS-PAGE)
Target Names
ADGRD1
Uniprot NO.
Species
Homo sapiens (Human)
Source
Yeast
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Orphan receptor. Signals via G(s)-alpha family of G-proteins. Has protumorigenic function especially in glioblastoma.
Gene References into Functions
  1. The results show that a broad spectrum of functionally relevant ADGRD1 variants is present in the human population which may cause clinically relevant phenotypes, while being compatible with life when heterozygous. PMID:27516204
  2. Cell adhesion receptor GPR133 couples to Gs protein PMID:22025619
  3. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID:20379614
  4. A role for GPR133 protein in affecting the length of the electrocardiographic RR interval and heart rate. PMID:20031603
  5. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID:20031603
  6. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID:19729412

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Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
Tissue Specificity
Up-regulated in CD133(+) cell population of glioblastoma.
Database Links

HGNC: 19893

UNIGENE: Hs.719239

KEGG: hsa:283383

STRING: 9606.ENSP00000261654

OMIM: 613639

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