Recombinant Human Probable G-protein coupled receptor 125 (GPR125), partial

Product Details

Abbreviation
GPR125
Purity
>85% (SDS-PAGE)
Target Names
ADGRA3
Uniprot NO.
Species
Homo sapiens (Human)
Source
Yeast
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Orphan receptor that may have a role in planar cell polarity pathway.
Gene References into Functions
  1. GPR125 overexpression inhibited the beta-catenin transcriptional activity, and down-regulated the expression levels of the Wnt downstream proteins-Axin2, c-Myc, cylinD1, and lef-1. PMID:30231258
  2. ID4 and GPR125 are expressed on partially overlapping spermatogonial populations and are more broadly expressed in normal adult human testis. ID4 and GPR125 could be used for identifying previously unrecognized human spermatogonial subpopulations PMID:24902969

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Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
Database Links

HGNC: 13839

UNIGENE: Hs.684429

KEGG: hsa:166647

STRING: 9606.ENSP00000334952

OMIM: 612303

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