Recombinant Human Probable G-protein coupled receptor 116 (GPR116), partial

Product Details

Abbreviation
GPR116
Purity
>85% (SDS-PAGE)
Target Names
ADGRF5
Uniprot NO.
Species
Homo sapiens (Human)
Source
Yeast
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Receptor that plays a critical role in lung surfactant homeostasis. May play a role in controlling adipocyte function.
Gene References into Functions
  1. our study demonstrated that GPR116 was significantly upregulated in CRC tissues and could serve as an independent prognostic indicator for patients with CRC. PMID:28624786
  2. These findings show that GPR116 is crucial for the metastasis of breast cancer and support GPR116 as a potential prognostic marker and drug target against metastatic human breast cancer. PMID:24008316
  3. Observational study of gene-disease association. (HuGE Navigator) PMID:19913121
  4. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID:20628086
  5. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID:20379614
  6. SEA domain autoproteolysis accelerated by conformational strain. PMID:18308334
  7. SEA domain autoproteolysis accelerated by conformational strain: mechanistic aspects. PMID:18314133
  8. Clinical trial and genome-wide association study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID:18519826

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Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
Database Links

HGNC: 19030

UNIGENE: Hs.362806

KEGG: hsa:221395

STRING: 9606.ENSP00000265417

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