Recombinant Human Probable G-protein coupled receptor 110 (GPR110), partial

Product Details

Abbreviation
GPR110
Purity
>85% (SDS-PAGE)
Target Names
ADGRF1
Uniprot NO.
Alternative Names
G protein coupled receptor 110; G protein coupled receptor KPG_012; G protein coupled receptor PGR19; G-protein coupled receptor KPG_012; G-protein coupled receptor PGR19; GP110_HUMAN; GPR110; HGPCR36; KPG_012; PGR19; Probable G protein coupled receptor 110; Probable G-protein coupled receptor 110
Species
Homo sapiens (Human)
Source
Yeast
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Orphan receptor.
Gene References into Functions
  1. Study demonstrated orphan G-protein coupled receptor 110 (GPR110, ADGRF1) as the synaptamide receptor, mediating synaptamide-induced bioactivity in a cAMP-dependent manner. PMID:27759003
  2. High GPR110 expression is associated with CRLF2-rearranged acute lymphoblastic leukemia. PMID:28866095
  3. ADGRF1 single-nucleotide polymorphisms role in susceptibility to non-small cell lung cancer PMID:28968839
  4. The results suggested the possible participation of STAT3 instead of ERK in the GPR110 signaling pathways and progression of glioma. PMID:28728843
  5. GPR56 and GPR110 are activated by exposure of a cryptic tethered agonist PMID:25918380
  6. GPR110 is an oncogene overexpressed in lung and prostate cancer PMID:20149256

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Subcellular Location
Cell membrane; Multi-pass membrane protein.; [Isoform 2]: Secreted.
Protein Families
G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
Tissue Specificity
Mainly expressed in the kidney. Up-regulated in lung adenocarcinomas and prostate cancers.
Database Links

HGNC: 18990

UNIGENE: Hs.733762

KEGG: hsa:266977

STRING: 9606.ENSP00000360299

OMIM: 617430

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