Recombinant Human Potassium voltage-gated channel subfamily A member 10 (KCNA10), partial

Product Details

Abbreviation
KCNA10
Purity
>85% (SDS-PAGE)
Target Names
KCNA10
Uniprot NO.
Alternative Names
KCNA10; Potassium voltage-gated channel subfamily A member 10; Voltage-gated potassium channel subunit Kv1.8
Species
Homo sapiens (Human)
Source
Yeast
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)
Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The channel activity is up-regulated by cAMP.
Gene References into Functions
  1. KCNA10 in human proximal tubular cells, glomerular and vascular endothelial cells, and also in vascular smooth muscle cells. PMID:12444201

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Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
Potassium channel family, A (Shaker) (TC 1.A.1.2) subfamily, Kv1.8/KCNA10 sub-subfamily
Tissue Specificity
Detected in kidney, in proximal tubules, glomerular endothelium, in vascular endothelium and in smooth muscle cells.
Database Links

HGNC: 6219

UNIGENE: Hs.248140

KEGG: hsa:3744

STRING: 9606.ENSP00000358786

OMIM: 602420

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