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Recombinant Human P2X purinoceptor 6 (P2RX6), partial

Recombinant Human P2X purinoceptor 6 (P2RX6), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

P2RX6

Uniprot NO.

O15547

Alternative Names

ATP receptor; P2RX6; P2RX6_HUMAN; P2RXL1; P2X purinoceptor 6; P2X6; P2XM; Purinergic receptor; Purinergic receptor P2X ligand gated ion channel 6; Purinergic receptor P2X like 1; Purinergic receptor P2X-like 1; Purinoceptor P2X6; Purinoreceptor P2X6; Skeletal muscle expressed P2X

Species

Homo sapiens (Human)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Receptor for ATP that acts as a ligand-gated ion channel.

Gene References into Functions

one subunit of P2X2 and two subunits of P2X3 form P2X2/3 heteromeric receptors, whereas two subunits of P2X2 and one subunit of P2X6 constitute P2X2/6 receptors PMID:22378790
Results show that P2X4 and P2X6 receptors are associated with VE-cadherin at HUVEC adherens junctions. PMID:12088286
P2X(2) receptors are trimers, whereas the P2X(6) receptor subunits do not form stable oligomers PMID:15657042

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Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Families

P2X receptor family

Tissue Specificity

Expressed predominantly in skeletal muscle.

Database Links

HGNC: 8538

UNIGENE: Hs.113275

KEGG: hsa:9127

STRING: 9606.ENSP00000416193