Recombinant Human Interleukin-17D (IL17D)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Abbreviation

IL17D

Purity

>85% (SDS-PAGE)

Target Names

IL17D

Uniprot NO.

Q8TAD2

Species

Homo sapiens (Human)

Source

Yeast

Expression Region

16-202

Target Protein Sequence

AGAPR AGRRPARPRG CADRPEELLE QLYGRLAAGV LSAFHHTLQL GPREQARNAS CPAGGRPADR RFRPPTNLRS VSPWAYRISY DPARYPRYLP EAYCLCRGCL TGLFGEEDVR FRSAPVYMPT VVLRRTPACA GGRSVYTEAY VTIPVGCTCV PEPEKDADSI NSSIDKQGAK LLLGPNDAPA GP
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

Submit a Review here

Target Background

Function(From Uniprot)

Induces expression of IL6, CXCL8/IL8, and CSF2/GM-CSF from endothelial cells.

Gene References into Functions

Nrf2 Induces IL-17D to mediate tumor and virus surveillance. PMID:27545889
Study of the expression of IL-17 provides theoretical support for the clinical treatment and prognosis prediction of ovarian epithelial tumor. PMID:28685546
Utilizing gene microarray analysis, authors found the cytokine interleukin 17D (IL-17D) was highly expressed in certain unedited tumors. PMID:24794441
These experiments were designed to investigate the effects of IL-17 upon the phenotype and function of human Natural Killer (NK) cells. PMID:23490420
IL-27 priming results in enhanced lipopolysaccharide-induced IL-6, tumor necrosis factor (TNF)-alpha, macrophage inflammatory protein (MIP)-1alpha, and MIP-1beta expression in human primary monocytes. PMID:22156348
IL-17D stimulates production of cytokines in endothelial cells in vitro and suppresses proliferation of myeloid progenitors in colony formation assays. PMID:12097364