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Recombinant Human Interferon-induced protein 44 (IFI44)

Recombinant Human Interferon-induced protein 44 (IFI44)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

IFI44

Purity

>85% (SDS-PAGE)

Target Names

IFI44

Uniprot NO.

Q8TCB0

Species

Homo sapiens (Human)

Source

Yeast

Expression Region

1-444

Target Protein Sequence

MAVTTRLTWL HEKILQNHFG GKRLSLLYKG SVHGFRNGVL LDRCCNQGPT LTVIYSEDHI IGAYAEESYQ EGKYASIILF ALQDTKISEW KLGLCTPETL FCCDVTKYNS PTNFQIDGRN RKVIMDLKTM ENLGLAQNCT ISIQDYEVFR CEDSLDERKI KGVIELRKSL LSALRTYEPY GSLVQQIRIL LLGPIGAGKS SFFNSVRSVF QGHVTHQALV GTNTTGISEK YRTYSIRDGK DGKYLPFILC DSLGLSEKEG GLCRDDIFYI LNGNIRDRYQ FNPMESIKLN HHDYIDSPSL KDRIHCVAFV FDASSIQYFS SQMIVKIKRI RRELVNAGVV HVALLTHVDS MDLITKGDLI EIERCEPVRS KLEEVQRKLG FALSDISVVS NYSSEWELDP VKDVLILSAL RRMLWAADDF LEDLPFEQIG NLREEIINCA QGKK
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function(From Uniprot)

This protein aggregates to form microtubular structures.

Gene References into Functions

IFI44 localizes to nuclei and suppresses HIV-1 LTR promoter. PMID:25776761
The restriction of Bunyamwera virus replication mediated by interferon is an accumulated effect of at least three interferon-stimulated genes viperin, MTAP44 and PKR. PMID:22896602
Binds and depletes intracellular GTP, abolishing extracellular signal-regulated kinase (ERK) signaling and resulting finally in cell cycle arrest. PMID:17784819

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Subcellular Location

Cytoplasm.

Protein Families

IFI44 family

Database Links

HGNC: 16938

UNIGENE: Hs.82316

KEGG: hsa:10561

STRING: 9606.ENSP00000359783

OMIM: 610468

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