Recombinant Human Histone H2B type F-M (H2BFM)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

H2BFM

Uniprot NO.

P0C1H6

Alternative Names

H2BW2; H2BFM; Histone H2B type F-M; Histone H2B.s; H2B/s

Species

Homo sapiens (Human)

Source

Yeast

Expression Region

1-257

Target Protein Sequence

MKCHAGSLSA NLPALKVTGW SRCVASRQPI TVGVCGPKRP LWPSSEKPFN FHTLAKLHDI GLGNDFLDMT LKAQQQKQKS HATIPKCPPL PWSPTVTLCS CYLMAAASAM AEASSETTSE EGQSIQEPKE ANSTKAQKQK RRGCRGSRRR HANRRGDSFG DSFTPYFPRV LKQVHQGLSL SQEAVSVMDS MIHDILDRIA TEAGQLAHYT KRVTITSRDI QMAVRLLLPG KMGKLAEAQG TNAALRTSLC AIWQQRK
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Subcellular Location

Nucleus. Chromosome.

Protein Families

Histone H2B family

Database Links

HGNC: 27867

UNIGENE: Hs.376474

KEGG: hsa:286436

STRING: 9606.ENSP00000347119

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