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Recombinant Human Fibroblast growth factor 16 (FGF16)

Recombinant Human Fibroblast growth factor 16 (FGF16)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

FGF16

Uniprot NO.

O43320

Alternative Names

FGF 16; FGF-16; Fgf16; FGF16_HUMAN; Fibroblast growth factor 16

Species

Homo sapiens (Human)

Source

Yeast

Expression Region

1-207

Target Protein Sequence

MAEVGGVFAS LDWDLHGFSS SLGNVPLADS PGFLNERLGQ IEGKLQRGSP TDFAHLKGIL RRRQLYCRTG FHLEIFPNGT VHGTRHDHSR FGILEFISLA VGLISIRGVD SGLYLGMNER GELYGSKKLT RECVFREQFE ENWYNTYAST LYKHSDSERQ YYVALNKDGS PREGYRTKRH QKFTHFLPRP VDPSKLPSMS RDLFHYR
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function(From Uniprot)

Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development.

Gene References into Functions

Experiments demonstrated FGF16 could promote proliferation of NCL-H460 cells by activating Akt, Erk1/2, and p38 MAPK signaling, whereas JNK had no significant effect. PMID:28409700
Identification of an FGF16 mutation in metacarpal 4-5 fusion. PMID:24878828
impaired FGF16 function may also be responsible for connective tissue symptoms in MF4 patients. PMID:24706454
Fgf-16 gene is a target for NF-kappaB activation in the postnatal heart. PMID:20097674
HUVEC clearly demonstrated chemotaxis towards FGF16. FGF16 enhanced cell migration in response to mechanical damage & failed to induce endothelial cell proliferation or sprouting in a three-dimensional in vitro angiogenesis assay. PMID:16756958