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Recombinant Human Endothelial cell-selective adhesion molecule (ESAM), partial

Recombinant Human Endothelial cell-selective adhesion molecule (ESAM), partial

Baculovirus
Mammalian cell

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Abbreviation

ESAM

Purity

>85% (SDS-PAGE)

Target Names

ESAM

Uniprot NO.

Q96AP7

Alternative Names

2310008D05Rik; Endothelial cell adhesion molecule; Endothelial cell selective adhesion molecule; Endothelial cell-selective adhesion molecule; Esam; ESAM_HUMAN; HUEL (C4orf1) interacting protein ; LP4791 protein ; W117m

Species

Homo sapiens (Human)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Can mediate aggregation most likely through a homophilic molecular interaction.

Gene References into Functions

sESAM levels associate with myocardial infarction, heart failure, and death after adjustment for demographic and clinical risk factors, but not after adjustment for kidney function. PMID:26523992
ESAM is a novel human hematopoietic stem cell marker associated with a subset of human leukemias PMID:26774386
Serum ESAM is higher in type 2 diabetes mellitus than in controls and parallels oxidative stress. PMID:24456423
sESAM is associated with albuminuria and reduced kidney function in patients with coronary artery disease in both cross-sectional and longitudinal analyses. PMID:24177327
ESAM regulates tumor metastasis through endothelial cell migration and tube formation in metastatic nodules. PMID:20153339
sESAM is a predictive biomarker and potential mediator of atherosclerosis. PMID:19759376