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Recombinant Human Bromodomain and WD repeat-containing protein 3 (BRWD3), partial

Recombinant Human Bromodomain and WD repeat-containing protein 3 (BRWD3), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

BRWD3

Purity

>85% (SDS-PAGE)

Target Names

BRWD3

Uniprot NO.

Q6RI45

Species

Homo sapiens (Human)

Source

Yeast

Expression Region

1-1802

Target Protein Sequence

MAAAPTQIEA ELYYLIARFL QSGPCNKSAQ VLVQELEEHQ LIPRRLDWEG KEHRRSFEDL VAANAHIPPD YLLKICERIG PLLDKEIPQS VPGVQTLLGV GRQSLLRDAK DCKSTLWNGS AFAALHRGRP PELPVNYVKP PNVVNITSAR QLTGCSRFGH IFPSSAYQHI KMHKRILGHL SSVYCVAFDR SGRRIFTGSD DCLVKIWATD DGRLLATLRG HSAEISDMAV NYENTLIAAG SCDKVVRVWC LRTCAPVAVL QGHSASITSI QFCPSTKGTN RYLTSTGADG TICFWQWHVK TMKFRDRPVK FTERSRPGVQ ISCSSFSSGG MFITTGSTDH VIRIYYLGSE VPEKIAELES HTDKVVAVQF CNNGDSLRFV SGSRDGTARI WQYQQQEWKS IVLDMATKMT GNNLPSGEDK ITKLKVTMVA WDRYDTTVIT AVNNFLLKVW NSITGQLLHT LSGHDDEVFV LEAHPFDQRI ILSAGHDGNI FIWDLDRGTK IRNYFNMIEG QGHGAVFDCK FSPDGNHFAC TDSHGHLLLF GFGCSKYYEK IPDQMFFHTD YRPLIRDANN YVLDEQTQQA PHLMPPPFLV DVDGNPHPTK FQRLVPGREN CKDEQLIPQL GYVANGDGEV VEQVIGQQTN DQDESILDGI IRELQREQDL RLINEGDVPH LPVNRAYSVN GALRSPNMDI SSSPNIRLRR HSSQIEGVRQ MHNNAPRSQM ATERDLMAWS RRVVVNELNN GVSRVQEECR TAKGDIEISL YTVEKKKKPS YTTQRNDYEP SCGRSLRRTQ RKRQHTYQTR SNIEHNSQAS CQNSGVQEDS DSSSEEDETV GTSDASVEDP VVEWQSESSS SDSSSEYSDW TADAGINLQP PKRQTRQTTR KICSSSDEEN LKSLEERQKK PKQTRKKKGG LVSIAGEPNE EWFAPQWILD TIPRRSPFVP QMGDELIYFR QGHEAYVRAV RKSKIYSVNL QKQPWNKMDL REQEFVKIVG IKYEVGPPTL CCLKLAFLDP ISGKMTGESF SIKYHDMPDV IDFLVLHQFY NEAKERNWQI GDRFRSIIDD AWWFGTVESQ QPFQPEYPDS SFQCYSVHWD NNEREKMSPW DMEPIPEGTA FPDEVGAGVP VSQEELTALL YKPQEGEWGA HSRDEECERV IQGINHLLSL DFASPFAVPV DLSAYPLYCT VVAYPTDLNT IRRRLENRFY RRISALMWEV RYIEHNARTF NEPDSPIVKA AKIVTDVLLR FIGDQSCTDI LDTYNKIKAE ERNSTDAEED TEIVDLDSDG PGTSSGRKVK CRGRRQSLKC NPDAWKKQCK ELLSLIYERE DSEPFRQPAD LLSYPGHQEQ EGESSESVVP ERQQDSSLSE DYQDVIDTPV DFSTVKETLE AGNYGSPLEF YKDVRQIFNN SKAYTSNKKS RIYSMMLRLS ALFESHIKNI ISEYKSAIQS QKRRRPRYRK RLRSSSSSLS SSGAPSPKGK QKQMKLQPKN DQNTSVSHAR TSSPFSSPVS DAAEGLSLYL LDDEPDGPFS SSSFGGYSRS GNSHDPGKAK SFRNRVLPVK QDHSLDGPLT NGDGREPRTG IKRKLLSASE EDENMGGEDK EKKETKEKSH LSTSESGELG SSLSSESTCG SDSDSESTSR TDQDYVDGDH DYSKFIQTRP KRKLRKQHGN GKRNWKTRGT GGRGRWGRWG RWSRGGRGRG GRGRGSRGRG GGGTRGRGRG RGGRGASRGA TRAKRARIAD DEFDTMFSGR FSRLPRIKTR NQGRRTVLYN DDSDNDNFVS TEDPLNLGTS RSGRVRKMTE KARVSHLMGW NY
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.

Gene References into Functions

BCL7A, BRWD3, and AUTS2 demonstrate significantly higher mutation frequencies among AA cases. These genes are all involved in translocations in B-cell malignancies. Moreover, we detected a significant difference in mutation frequency of TP53 and IRF4 with frequencies higher among CA cases. Our study provides rationale for interrogating diverse tumor cohorts to best understand tumor genomics across populations. PMID:29166413
A nonsense mutation in BRWD3 in a family with X-linked intellectual disability associated with macrocephaly. PMID:24462886
potential serological biomarker of breast cancer PMID:22024541
Includes the identification of truncating mutations in this gene that segregated with mental retardation in the families tested. PMID:19377476
BRWD3 is therefore a new gene implicated in the etiology of XLMR associated with macrocephaly and may cause disease by altering intracellular signaling pathways affecting cellular proliferation. PMID:17668385