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Recombinant Human Asialoglycoprotein receptor 2 (ASGR2), partial

Recombinant Human Asialoglycoprotein receptor 2 (ASGR2), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

ASGR2

Uniprot NO.

P07307

Species

Homo sapiens (Human)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.

Gene References into Functions

sH2a has the potential to be a uniquely sensitive and specific novel marker for liver fibrosis and function. PMID:22096539
trafficks intracellularly and forms homo-oligomers, but does not bind asialo-orosomucoid PMID:12089159

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Subcellular Location

Membrane; Single-pass type II membrane protein.

Tissue Specificity

Expressed exclusively in hepatic parenchymal cells.

Database Links

HGNC: 743

UNIGENE: Hs.654440

KEGG: hsa:433

STRING: 9606.ENSP00000347140

OMIM: 108361

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