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Recombinant Human Acid-sensing ion channel 4 (ASIC4), partial

Recombinant Human Acid-sensing ion channel 4 (ASIC4), partial

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MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

ASIC4

Purity

>85% (SDS-PAGE)

Target Names

ASIC4

Uniprot NO.

Q96FT7

Alternative Names

ASIC4; ACCN4; Acid-sensing ion channel 4; ASIC4; Amiloride-sensitive cation channel 4; Amiloride-sensitive cation channel 4; pituitary

Species

Homo sapiens (Human)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity.

Gene References into Functions

Acid-sensing ion channel (ASIC) 4 predominantly localizes to an early endosome-related organelle upon heterologous expression PMID:26667795
Data show that transfected ASIC4 is targeted to the plasma membrane in CHO-K1 cells, where it associates with ASIC1a and downregulates exogenous ASIC1a expression. PMID:18662336

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Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Families

Amiloride-sensitive sodium channel (TC 1.A.6) family, ASIC4 subfamily

Tissue Specificity

Expressed in pituitary gland. Weakly expressed in brain, vestibular system and organ of Corti.

Database Links

HGNC: 21263

UNIGENE: Hs.87469

KEGG: hsa:55515

STRING: 9606.ENSP00000326627