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Recombinant Horse Vascular endothelial growth factor A (VEGFA)

Recombinant Horse Vascular endothelial growth factor A (VEGFA)

Baculovirus
Mammalian cell

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

VEGFA

Purity

>85% (SDS-PAGE)

Target Names

VEGFA

Uniprot NO.

Q9GKR0

Species

Equus caballus (Horse)

Source

Yeast

Expression Region

27-190

Target Protein Sequence

APMA EGEHKTHEVV KFMDVYQRSY CRPIETLVDI FQEYPDEIEY IFKPSCVPLM RCGGCCNDEG LECVPTAEFN ITMQIMRIKP HQSQHIGEMS FLQHSKCECR PKKDKARQEN PCGPCSERRK HLFVQDPQTC KCSCKNTDSR CKARQLELNE RTCRCDKPRR
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development.

Gene References into Functions

Peripheral Blood-Derived Mesenchymal Stromal Cells Promote Angiogenesis via Paracrine Stimulation of Vascular Endothelial Growth Factor Secretion PMID:25313202
TNF may up-regulate VEGF and stimulate angiogenesis in the mare early corpus luteum. PMID:22492973

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Subcellular Location

Secreted.

Protein Families

PDGF/VEGF growth factor family

Database Links

UNIGENE: Eca.12648

KEGG: ecb:100033839

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