Recombinant Horse Gelsolin (GSN), partial

Product Details

Abbreviation
GSN
Purity
>85% (SDS-PAGE)
Target Names
GSN
Uniprot NO.
Alternative Names
GSNGelsolin; Actin-depolymerizing factor; ADF; Brevin
Species
Equus caballus (Horse)
Source
Yeast
Expression Region
1-731
Target Protein Sequence
MVVEHPEFLK AGKEPGLQIW RVEKFDLVPV PPNLYGDFFT GDAYVILKTV QLRNGILQYD LHYWLGNECS QDESGAAAIF TVQLDDYLNG RAVQHREVQG FESATFLGYF KSGLKYKKGG VASGFKHVVP NEVVVQRLLQ VKGRRVVRAT EVPVSWESFN NGDCFILDLG NNIYQWCGSK SNRFERLKAT QVSKGIRDNE RSGRAQVSVF EEGAEPEAML QVLGPKPTLP EATEDTVKED AANRKLAKLY KVSNGAGPMV VSLVADENPF AQGALRSEDC FILDHGKDGK IFVWKGKQAN MEERKAALKT ASDFISKMDY PKQTQVSVLP EGGETPLFRQ FFKNWRDPDQ TEGLGLAYLS SHIAHVERVP FDAATLHTST AMAAQHGMDD DGTGQKQIWR VEGSNKVPVD PATYGQFYGG DSYIILYNYR HGSRQGQIIY NWQGAQSTQD EVAASAILTA QLDEELGGTP VQSRVVQGKE PAHLMSLFGG KPMIVYKGGT SREGGQTAPA STRLFQVRAS SSGATRAVEI IPKAGALNSN DAFVLKTPSA AYLWVGAGAS EAEKTGAQEL LRVLRAQPVQ VAEGSEPDSF WEALGGKATY RTSPRLKDKK MDAHPPRLFA CSNKIGRFVI EEVPGEFMQE DLATDDVMLL DTWDQVFVWV GKDSQDEEKT EALTSAKRYI DTDPAHRDRR TPITVVKQGF EPPSFVGWFL GWDDSYWSVD PLDRALAELA A
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
Gene References into Functions
  1. Ca2+ binding by domain 2 plays a critical role in the activation and stabilization of gelsolin PMID:19666512

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Subcellular Location
Cytoplasm, cytoskeleton.
Protein Families
Villin/gelsolin family
Database Links

UNIGENE: Eca.2517

KEGG: ecb:100034186

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