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Recombinant Guinea pig Peroxisome proliferator-activated receptor alpha (PPARA)

Recombinant Guinea pig Peroxisome proliferator-activated receptor alpha (PPARA)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

PPARA

Uniprot NO.

O35507

Species

Cavia porcellus (Guinea pig)

Source

Yeast

Expression Region

1-467

Target Protein Sequence

MVDMESPLCP LSPLEAEDLE SPLSEYFLQE MGTIQDISRS LGEDSSGSFG FPEYQYLGSG PGSDGSVITD TLSPASSPSS VSYPEVPCGV DEPPSSALNI ECRICGDKAS GYHYGVHACE GCKGFFRRTI RLKLVYDKCD RSCKIQKKNR NKCQYCRFHK CLSVGMSHNA IRFGRMPRSE KAKLKAEVLT CDRDSEGAET ADLKSLAKRI YEAYLKNFHM NKVKARIILA GKTSSHPLFV IHDMETLCTA EKTLMAKVVS DGIRDKEAEV RIFHCCQCVS VETVTNLTEF AKAIPGFASL DLNDQVTLLK YGVYEAIFTM LSSTMNKDGM LVAYGHGFIT REFLKNLRKP FCDMMEPKFN FAMKFNALEL DDSDISLFVA AIICCGDRPG LLNIDHIEKM QEAIVHVLKL HLQSNHPDDT FLFPKLLQKL ADLRQLVTEH AQLVQVIKTE SDAALHPLLQ EIYRDMY
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.

Subcellular Location

Nucleus.

Protein Families

Nuclear hormone receptor family, NR1 subfamily

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