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Recombinant Equine herpesvirus 1 Major DNA-binding protein (31), partial

Recombinant Equine herpesvirus 1 Major DNA-binding protein (31), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

DBP

Uniprot NO.

P28932

Species

Equine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus)

Source

Yeast

Expression Region

1-1209

Target Protein Sequence

MESAPKTVSL PVSPLGYVYA RQKASLQTGT VSLTAARSVD SDLAVLPVIR GLTVEQTFTT NVAVVAGSKT TGLGGTGITL KLTPSHFNPN AFVFYGGSVI GASSNAPNLT RACEAARRRF GFSAFSSPPV ENAVETSGEE ICASLNLSPE TTALYLVVTE SFKEMVYVCN TFLHYGGTST VTIDGQDAMK IPIYPVQLYM PDVNRLASEP FNAKHRSIGD EFVYSRPFFN SDLCRLLHGY VLGPAAVALR VRNLDGVARG AAHLALDENH EGSVLPQDVT FTLFDSTQGN AGKGSGRAQR QGDGSGSKNS ASSGIERRLA SVMAADTALS VDSIMGAGIY DTELPSVEDW PVLSSGDDTE SLEALGAYAA RLSGLVGAMV FSANSVLYMT EVDDGGPADG KDGSNPSYHR FYLIAAPYVA GNPQTDKDGR VLPHTADQQA APINGSNQEF SLDYLALACG FCPQILARLL FYLERCDAGT FGGRNETDAL RYLANTLESD VPCGLCNQAT RPACAHTTLH RLRQRLPRFG APVRAPIGIF GTMNSAYSDC DVLGNYASYG ALKRPNDNEA PKSIMQDTYR ATMERLVNEL EQAKLIDKET LAQASPCSAP TSVVHDQASF IGLLSNIKDT IEGAAEQFMR TLVEARDFKI REGLADANHT MSISLDPYSS SFCPVTSFLA RRTVFAVLQD LVLSQCHCLF YGQSVEGRNF RNQFQPVLRR RFLDMLNGGF ITAKTVTVTV SDSGVLAPDL TRPASEPPTK DYDGDMARVS MEVLRDLRVK NRVLFSNGGA NMSEAARARV AGMASAYRRP DKGSNILNGA VGFLVKQYHG VLFPRGHPPG IDTPNPQWFW TLLQRNQMPA RLLSKEDIET ITAIKRFSDE YSAINFINLT PNNIGELAQF YFANLVLKYC DHSQYFINGL TAIVVGSRRP RDPAAVLAWI DRTINGAADV EPAAQEVLQR LGSNPAAWTG TFTSTNMVRY VMDQRPMVVI GLSISKYNGS AGNNRVFQAG NWNGLNGGKN VCPLMAFDRT RRFVLACPRV GFTCEAGGFG TGVRENTLSE QVRGIVSEGG PMVQTAVFAA VLHALGARTQ HLAVDDWIGL VDDEFLAASL DALNATVVDQ FGEWSVEAAQ ELVKNMEAQT TAGAVAAGEG AFDFGACVGD TPQQSTSAFN GGLAMAAAPA GQKRSLPDDI LFDMGAPPEK KSGLTFDML
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Plays several crucial roles in viral infection. Participates in the opening of the viral DNA origin to initiate replication by interacting with the origin-binding protein. May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation. Promotes viral DNA recombination by performing strand-transfer, characterized by the ability to transfer a DNA strand from a linear duplex to a complementary single-stranded DNA circle. Can also catalyze the renaturation of complementary single strands. Additionally, reorganizes the host cell nucleus, leading to the formation of prereplicative sites and replication compartments. This process is driven by the protein which can form double-helical filaments in the absence of DNA.

Subcellular Location

Host nucleus.

Protein Families

Herpesviridae major DNA-binding protein family

Database Links

KEGG: vg:1487543

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