Recombinant Drosophila melanogaster Superoxide dismutase [Cu-Zn] (Sod)

Product Details

Purity
>85% (SDS-PAGE)
Target Names
Sod
Uniprot NO.
Alternative Names
Sod1; Sod; CG11793; Superoxide dismutase [Cu-Zn]; EC 1.15.1.1; Superoxide dismutase 1
Species
Drosophila melanogaster (Fruit fly)
Source
Yeast
Expression Region
2-153
Target Protein Sequence
VVKAVCVIN GDAKGTVFFE QESSGTPVKV SGEVCGLAKG LHGFHVHEFG DNTNGCMSSG PHFNPYGKEH GAPVDENRHL GDLGNIEATG DCPTKVNITD SKITLFGADS IIGRTVVVHA DADDLGQGGH ELSKSTGNAG ARIGCGVIGI AKV
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Full Length of Mature Protein
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Gene References into Functions
  1. the cytosolic SOD-null syndrome is largely consistent across sex and genetic background, but also significantly influenced by both. PMID:28624774
  2. Expression of zinc-deficient human superoxide dismutase in Drosophila neurons produces a locomotor defect linked to mitochondrial dysfunction. PMID:23601674
  3. curcumin increases mean lifespan of Drosophila via regulating gene expression of the key enzyme SOD and reducing accumulation of MDA and lipid peroxidation. PMID:22653297
  4. The activity of carbohydrate metabolizing enzymes, lipid and triglyceride concentration, and steady state NADPH:NADP(+) in SOD1-null and control transgenic rescue flies, was analysed. PMID:21909438
  5. survey of DNA sequence polymorphisms PMID:12578968
  6. A 1140 base pair region, composed of the single sod1 intron along with exon 2, was found to be essential for permitting spatial and temporal expression patterns that approximate normal endogenous expression. PMID:15019982
  7. Cu/Zn superoxide dismutase has a role in preventing spontaneous DNA damage PMID:15644960
  8. Instability of superoxide dismutase 1 of Drosophila in mutants deficient for its cognate copper chaperone PMID:18948262
  9. switching SOD1-deficient flies from normoxia into hypoxia fails to alter their mortality PMID:18983909

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Subcellular Location
Cytoplasm.
Protein Families
Cu-Zn superoxide dismutase family
Database Links

UNIGENE: Dm.926

KEGG: dme:Dmel_CG11793

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