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Recombinant Drosophila melanogaster Protein dead ringer (retn), partial

Recombinant Drosophila melanogaster Protein dead ringer (retn), partial

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Source
Conjugate
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Target Background

Product Details

Abbreviation

retn

Purity

>85% (SDS-PAGE)

Target Names

retn

Uniprot NO.

Q24573

Alternative Names

retn; dri; CG5403Protein dead ringer; Protein retained

Species

Drosophila melanogaster (Fruit fly)

Source

Yeast

Expression Region

1-911

Target Protein Sequence

MQLRVHPTMD CSGRSTSNIE RDSDLGDDLS HGDRTDDEMR DCDSVDGEHH QLSAKAAIAA RLSHTVSGGG GSFASPEPQT ELPLSHHHQL PPNHPLNALG SFMGIGGLHS IPNLQHSDVL EKLKMQVRDM KVGLMEQDYA AAAHAAAFGA NMLPTTISSG FPLPHNSVAF GHVTSSPSGG NGSSYNGGTT PTNSSNSNAT TNGGGTAGPG GTGGSGGGGG GGGGGGGGVG GHQFSFASPT AAPSGKEARH FAANSASNSS TSSEASNSSQ QNNGWSFEEQ FKQVRQLYEI NDDPKRKEFL DDLFSFMQKR GTPINRLPIM AKSVLDLYEL YNLVIARGGL VDVINKKLWQ EIIKGLHLPS SITSAAFTLR TQYMKYLYPY ECEKKNLSTP AELQAAIDGN RREGRRSSYG QYEAMHNQMP MTPISRPSLP GGMQQMSPLA LVTHAAVANN QQAQAAAAAA AAHHRLMGAP AFGQMPNLVK QEIESRMMEY LQLIQAKKEQ GMPPVLGGNH PHQQQHSQQQ QQQQHHHQQQ QQQQSQQQHH LQQQRQRSQS PDLSKHEALS AQVALWHMYH NNNSPPGSAH TSPQQREALN LSDSPPNLTN IKREREREPT PEPVDQDDKF VDQPPPAKRV GSGLLPPGFP ANFYLNPHNM AAVAAAAGFH HPSMGHQQDA ASEGEPEDDY AHGEHNTTGN SSSMHDDSEP QQMNGHHHHQ THHLDKSDDS AIENSPTTST TTGGSVGHRH SSPVSTKKKG GAKPQSGGKD VPTEDKDASS SGKLNPLETL SLLSGMQFQV ARNGTGDNGE PQLIVNLELN GVKYSGVLVA NVPLSQSETR TSSPCHAEAP TVEEEKDEEE EEEPKAAEEE SHRSPVKQEN EDVDQDMEGS EVLLNGGASA VGGAGAGVGV GVPLLKDAVV S
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Transcription factor which is a downstream target of gcm and repo. Directly or indirectly activates the transcription of locos and pros, which are essential for the development of some glial cells. Plays an essential role in defining the cell shape and migration characteristics of longitudinal glia that enable them to establish a normal axon scaffold.

Gene References into Functions

Dead ringer's preference for AT-rich DNA originates from three positions within the ARID fold that form energetically significant contacts to an adenine-thymine base step. PMID:11867548
RETN has a role in Drosophila preblastoderm syncytial mitoses PMID:12141428
Data suggest that Drosphila dead ringer is an important regulator of the late development of longitudinal glia. PMID:12620977
retained/dead ringer is necessary for neuronal pathfinding, female receptivity and repression of fruitless independent male courtship behaviors PMID:15576402

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Subcellular Location

Nucleus.

Tissue Specificity

Present in the pharyngeal muscles, hindgut epithelium, amnioserosa, ring gland, midgut-hindgut junction, posterior region of each brain lobe, longitudinal glial cells of the CNS and the salivary gland duct of germ-band retracted embryos.

Database Links

UNIGENE: Dm.20640

KEGG: dme:Dmel_CG5403

STRING: 7227.FBpp0071982

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