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Recombinant Drosophila melanogaster Nuclear RNA export factor 2 (nxf2), partial

Recombinant Drosophila melanogaster Nuclear RNA export factor 2 (nxf2), partial

Mammalian cell

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

nxf2

Purity

>85% (SDS-PAGE)

Target Names

nxf2

Uniprot NO.

Q9VV73

Alternative Names

nxf2; CG4118; Nuclear RNA export factor 2

Species

Drosophila melanogaster (Fruit fly)

Source

Yeast

Expression Region

1-841

Target Protein Sequence

MPNQMRVLDF GDGSVPIQLD YPDSKIFSKC SSYGDRVPGT HWNEITVHHK GRLEYSPNPE QIILDALYQA IDGADFFPVF YQRGKNMDTM LVRNCKAAID KLFKQRLSIN LKGGASIPIS IQLGVAQYQR HQITPTFHIA RVVTRLMKQL IQRDGVDGLL NLDNFGSHPE FKNLVVSLGN PSILMNVCQV IHNDDNERFR LNGFILSNNR IRDIRPLTLL ANVDYALLDL RGNKIKSAER LCRALEQFRA RELLLENNPI VKISNFPANI KSLESNFELV DGKPFNMLHK IFSPLDVEID LEVDGARIDT NNMWKLPEFE NSQHWHAFMI PDPSHEFNQE VFFDFFFIRL DPTLSNFYPC YYKYINTEHV FLVRNCFDQI AHLVNNCNLE MTIPTGDRIF RYYLRMNVST VKQHHVDPEE CIQKAVSQCY VAQNRMLNLE RFHSRECLKD VMVSLSSPKI LTYVLSVASR KFMTTCSEIR LCHNKVLVLD GAHVLGMMGC LRAVDLSHNW VQDLSSIHSL GNLPLKSLVL HGNKLCRNYR LPSEYVRAVK EVFPQLTTLD GVDLQTNPGQ SLQKNFLCDT GAYELVGAFL ENYLREFEND EFRHNLYKYY SENSIFTLTC NYNVVQNHQT PKILQRLSKY NRHARNLRNK DYSKASDGVF FGCTYIVEIL LQLPRVTHDF HSLQTDVMHY NGKGAVIYVA GLLRDEPPST RNGHGSKTDI GGVLLGFSRQ FVVTFDEANL GLGKRARRLK IANERLHITN PSKTAIRNAF SVNFPDPSER QAEEDSLDVK DHKLLLFQEV TGLISTWVTS IVEEADWDFE RALKLFIQKN ADHEIPDLAF A
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

May be involved in the export of mRNA from the nucleus to the cytoplasm. In the ovaries, forms a complex with nxf2, piwi and Nxt1 which acts as effectors of cotranscriptional transposon silencing. On recruitment to a target transcript, interacts with single stranded RNA, thereby anchoring the complex via the nascent target transcript to chromatin and allowing Panx to recruit silencing effectors to establishing repressive heterochromatin at transposon loci. Does not affect piRNA biogenesis. The interaction with Panx stabilizes the nuclear protein complex. Does not bind nucleoporins, but regulates sbr/Nxf1 binding to nucleoporins and, indirectly, transposon exports.

Subcellular Location

Cytoplasm. Nucleus. Nucleus, nucleoplasm.

Protein Families

NXF family

Tissue Specificity

Expressed in female gonads (at protein level). Expressed ubiquitously.

Database Links

UNIGENE: Dm.2730

KEGG: dme:Dmel_CG4118

STRING: 7227.FBpp0088483

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