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Recombinant Drosophila melanogaster DNA repair protein RAD50 (rad50), partial

Recombinant Drosophila melanogaster DNA repair protein RAD50 (rad50), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

rad50

Purity

>85% (SDS-PAGE)

Target Names

rad50

Uniprot NO.

Q9W252

Alternative Names

rad50; CG6339; DNA repair protein RAD50; EC 3.6.-.-

Species

Drosophila melanogaster (Fruit fly)

Source

Yeast

Expression Region

1-1318

Target Protein Sequence

MSSIESLSIQ GIRSFGTYAD DLQSIKFSSP VTLILGENGC GKTTVVECLK YALTGECPPG SDRGKSFVHD PKIFGLNEVL AQIKMQVRDR RGAQVSICRT MKVSKKRNKM SFETMDSTIN FLTGAGQSKR EKQDSLSGRS VDIDVAISDF MGVSKAIINN VLFCHQEDSS WPLDESKKLK EKFDAIFGIT EYNKALDKII KLRKEAMEEL KIKEANIKHV AYLKQEMEVK TLNLQKAQRK CDAIKAQCSE CEEEMKPIEA RLVEIRNVEF EIGKYQAQKV EMDTKHKNCK DQISTLTLKI KKPFRGTLDE LDQEISNFDQ RMLEMRQKRT EVEGDLSQIK RSSVAEQEKL GTQDRKHCLA KQRHQSELAC RAQLLKRVKE FCRELHIPID CDLVEQPEKM GEVLRDIEAM IITKHCEITE IVEQNEKADR SRQVKIDELR IELTKSEQSV TAQEKQRESS KRESETLGVE IKKIETSMQD LKKLEKEINE VNELYESATK NIDQQAIKDA IARKKASIAE NQIQFKKLDE QLTFLGSMAK LVAECSLKQK ELDKKNQEVH RVRSRHSDHF GKLFKEPITC NYRRSMQVVY EKLRREIQEL NEKANTQKLK EQSYEIKRKN LISDISRMEK ELKDSEELIY QKCRSTPYDD LLERSKTTIS KLQFDHGALK SSEALYKKYI QKMDEEPSCP LCHHNMTSDE ACDLTSELTD EIQKLPDNIT RAEKALKAEQ IKYENLLQLK PTILKVKELK DSLPQKKEEL KKVEELLGDS VSEYETLIAL IGEPTHNMEL ANSMMGDMSL LDEALKDSAR LTKDLDLQKG QLPASYDSSV SMDDLQAEKS KVSKELETER KELESAQNAV QQQMDALNRL REKKNSLKDR QIHLREGLQS LPQLKERLEK LNSFLTTVAS EISELKAKIQ PLKLNLRAAI EEKERLKKSE SEKLAQLNSK YNSYKSTDHD IQRLNKEAED YAKLDLRNEI KKLDEIIMAS KDKLRKLEAE ISLKTDELET IKTECSNQQT VERDLKDNRE LKQLEDKEAK LRESCQVLDK QLGNLDFHSV SKEKVNLTKQ RDKATVRKGE LLGQLGEIHS QVNKLQREID EPRFKESLKN FRKANYEIEV TRLCIEDLGQ YRLALEWALI QFHSEKMEMI NRLIREYWRK IYRGNDIDYI QVKTDEVSSD ASADRRKTYN YRVVQSKNYS EIEMRGRCSA GQRVLASLII RLALAETFSS NCGVLALDEP TTNLDRANIN SLCEALNCIV EERQSQSNFM LIIITHDENF VSSLGKITSY HRVFRNEECK SVIRRVEAGP SKKALIDQ
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Essential component of the MRN complex, a complex that possesses single-stranded DNA endonuclease and 3' to 5' exonuclease activities, and plays a central role in double-strand break (DSB) repair. The complex participates in processes such as DNA recombination, DNA repair, genome stability, telomere integrity and meiosis. The MRN complex may protect telomeres by facilitating recruitment of HOAP and HP1 at chromosome ends. In the complex, it mediates the ATP-binding and is probably required to bind DNA ends and hold them in close proximity.

Subcellular Location

Nucleus. Chromosome. Chromosome, telomere. Note=Uniformly distributed along mitotic chromosomes.

Protein Families

SMC family, RAD50 subfamily

Database Links

KEGG: dme:Dmel_CG6339

STRING: 7227.FBpp0290882

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