Recombinant Drosophila melanogaster Autophagy-related protein 13 homolog (Atg13), partial

Product Details

Abbreviation
Atg13
Purity
>85% (SDS-PAGE)
Target Names
Atg13
Uniprot NO.
Alternative Names
Atg13; CG7331Autophagy-related protein 13 homolog
Species
Drosophila melanogaster (Fruit fly)
Source
Yeast
Expression Region
1-523
Target Protein Sequence
MSAQRLNAAE RDLEKFIKFL VLKSTQVVVQ SRLGEKMQTQ CNPLAGSDWF NIAVQDHPEV LDETKRALNL KTGESILQRL PLCVEISLKT TEGDQMVLEV WSLDLLQPQN GASPATNDLN PEGQTLKAAH AIYNRMGIML KSLISLTRTT PAYKLSRRQC PDSYGIFYRI YVDRPQVHTL GEGHKHVKIG QLSTIVGSLV MSVAYRTKLT ISPTAAQSES NTIMLKSDHF RPATDANTPG NQQQTQNGTV VAKKLGLGAL NPAQGTADRR FIDIEKPLRP GAFTDMGKLK QYTEDDFVLP ETPPFEWLLR GRGSVESLNR LDNNSVASVN ISNNNNSTQD SKFNQISNLN NNSAGFKSFE KNSENSVSPI KSLLIPASAT ATYRHHSEPS LQPPPDDDNL LKELHFPFAS PTSHVNDLAK FYRECYHAPP LKGLNELQAE ISSISSTPPA SSGSGGVAAC GPTAAATAIA TSSADASAMD DLSRQLEQFE TSLEDYDKLV SQFGLTGSSS TGSRSSGGLQ MSN
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)
Autophagy factor required for autophagosome formation. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of Atg13 and Atg1. The Atg1-Atg13 complex functions at multiple levels to mediate and adjust nutrient-dependent autophagic signaling. Involved in the autophagic degradation of dBruce which controls DNA fragmentation in nurse cells.
Gene References into Functions
  1. Knockout of Atg1 or Atg13 (CG7331) results in a similar, selective defect in autophagy in response to TOR inactivation. PMID:19225150

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Subcellular Location
Cytoplasm, cytosol. Preautophagosomal structure.
Protein Families
ATG13 family, Metazoan subfamily
Database Links

UNIGENE: Dm.3718

KEGG: dme:Dmel_CG7331

STRING: 7227.FBpp0081333

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