Recombinant Dog Stromelysin-1 (MMP3)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Abbreviation

MMP3

Purity

>85% (SDS-PAGE)

Target Names

MMP3

Uniprot NO.

Q6Y4Q5

Species

Canis lupus familiaris (Dog) (Canis familiaris)

Source

Yeast

Expression Region

100-478

Target Protein Sequence

F TTFPGMPKWR KTHLTYRIMN YTPDLPRDAV DSAIEKALNV WKEVTPLTFS RTDEGEADIK ISFAVRDHGD FNPFDGPGNV LGHAYPPGPG IYGDAHFDDD EQWTSDTSGT NLFLVAAHEL GHSLGLFHSA DPSALMYPVY NVLADLARFH LSQDDVNGIQ SLYGGPPSDS SNDPVVPTES VPPGPGTPAA CDPTLSFDAI STLRGEFLFF KDRHFWRKSL RTLEPGFYLI SSFWPSLPSG LDAAYEETSK DIVFIFKGNQ FWAMRGTEVQ AGYPKGIHTL GFPPTVKKID AAVFDKEKKK TYFFVGDKYW RFDEKRQSME PGFPKQIAED FPGVDSKVDA AFEAFGFYYF FNGSSQLEFD PNAKKVTHVL KSNSWLNC
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.

Gene References into Functions

Findings suggested that increased TGF-beta3 and MMP-3 contribute to the pathogenesis of valvular degeneration associated with chronic mitral valve disease. PMID:21281193
Both mRNA transcript levels and the activities of MMP-3 and MMP-7 are elevated in X-linked Alport syndrome (XLAS) kidneys from dogs. PMID:15782307

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Subcellular Location

Secreted, extracellular space, extracellular matrix.

Protein Families

Peptidase M10A family

Database Links

UNIGENE: Cfa.3447

KEGG: cfa:403445

STRING: 9615.ENSCAFP00000022195

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