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Recombinant Dog Pro-epidermal growth factor (EGF), partial

Recombinant Dog Pro-epidermal growth factor (EGF), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

EGF

Purity

>85% (SDS-PAGE)

Target Names

EGF

Uniprot NO.

Q9BEA0

Alternative Names

EGFPro-epidermal growth factor; EGF) [Cleaved into: Epidermal growth factor]

Species

Canis lupus familiaris (Dog) (Canis familiaris)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.

Gene References into Functions

FGF2 and EGF Are Required for Self-Renewal and Organoid Formation of Canine Normal and Tumor Breast Stem Cells PMID:27632571
epidermal growth factor, transforming growth factor-alpha and EGF receptor may be involved in testicular maturation and function in the dog PMID:26498203
Matrix stiffening significantly sensitizes cells to EGF and enables the loss of contact inhibition. PMID:21429934
EGF-based signaling cascades phosphorylate Cav1 and have roles in caveolae assembly PMID:16332692
In malignant tumours (non-IMC and IMC), a strong correlation was observed between EGF and: progesterone, 17beta-estradiol, androstenedione, and dehydroepiandrosterone PMID:19429455