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Recombinant Dog Leukemia inhibitory factor receptor (LIFR), partial

Recombinant Dog Leukemia inhibitory factor receptor (LIFR), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

LIFR

Purity

>85% (SDS-PAGE)

Target Names

LIFR

Uniprot NO.

Q5XNR9

Species

Canis lupus familiaris (Dog) (Canis familiaris)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.

Gene References into Functions

data show that LIFR is highly co-expressed with adrenocorticotropic hormone (ACTH) and alpha-melanocyte-stimulating hormone (alpha-MSH) in the canine pituitary gland and in corticotrope adenomas PMID:20036483
each subunit of the CNTF receptor complex has a distinct distribution in polarised cells which may reflect the different roles the respective cytokines play in vivo PMID:15054106
There was no allelic association between a polymorphic microsatellite marker and pituitary dwarfism in German Shepherd dogs in this study. PMID:16624355

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Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Protein Families

Type I cytokine receptor family, Type 2 subfamily

Database Links

UNIGENE: Cfa.11570

KEGG: cfa:449478

STRING: 9615.ENSCAFP00000027533

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