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Recombinant Dog Hematopoietic progenitor cell antigen CD34 (CD34), partial

Recombinant Dog Hematopoietic progenitor cell antigen CD34 (CD34), partial

Code
MSDS	MSDS
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

CD34

Uniprot NO.

Q28270

Species

Canis lupus familiaris (Dog) (Canis familiaris)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Description

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Target Background

Function

Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.

Gene References into Functions

The gross, histologic, and immunohistochemical features of gastrointestinal stromal tumors, especially the expression of CD34 and Ki67, are reported. PMID:20826846
CD34+ cells exerted better antithrombogenic property than unfractioned mononuclear cells after seeding onto the small caliber vessel grafts. PMID:21124286

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Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Families

CD34 family

Tissue Specificity

Selectively expressed on hematopoietic progenitor cells and vascular endothelium.

Database Links

UNIGENE: Cfa.3771

KEGG: cfa:415130

STRING: 9615.ENSCAFP00000017250

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