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Recombinant Dog Ciliary neurotrophic factor receptor subunit alpha (CNTFR)

Recombinant Dog Ciliary neurotrophic factor receptor subunit alpha (CNTFR)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

CNTFR

Purity

>85% (SDS-PAGE)

Target Names

CNTFR

Uniprot NO.

Q71DR4

Alternative Names

CNTFRCiliary neurotrophic factor receptor subunit alpha; CNTF receptor subunit alpha; CNTFR-alpha

Species

Canis lupus familiaris (Dog) (Canis familiaris)

Source

Yeast

Expression Region

23-342

Target Protein Sequence

QRHSPQEA PHVQYERLGS DVTLPCGTAN WDAAVTWRVN GTDLALDLLN GSQLVLHGLE LGHSGLYACF HRDSWHLRHQ VLLHVGLPPR EPVLSCRSNT YPKGFYCSWH LPTPTYIPNT FNVTVLHGSK IMVCEKDPAL KNRCHIRYMH LFSTIKYKVS ISVSNALGHN ATAITFDEFT IVKPDPPENV VARPVPSNPR RLEVTWQTPS TWPDPESFPL KFFLRYRPLI LDQWQHVELS DGTTHTITDA YAGKEYIIQV AAKDYEIGTW SDWSVAAHAT PWTEEPRHLT TEAQAPETTT STTSSLAPPP TTKICDPGEL GS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Binds to CNTF. The alpha subunit provides the receptor specificity.

Gene References into Functions

each subunit of the CNTF receptor complex has a distinct distribution in polarised cells which may reflect the different roles the respective cytokines play in vivo PMID:15054106

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Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor.

Protein Families

Type I cytokine receptor family, Type 3 subfamily

Tissue Specificity

Expressed in retina, brain, spleen, lung, liver and kidney. In the retina it is highly expressed by photoreceptors, but also found in the RPE, inner nuclear layer and ganglion cells.

Database Links

UNIGENE: Cfa.3908

KEGG: cfa:442941

STRING: 9615.ENSCAFP00000002838

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