Recombinant Dog C-C motif chemokine 28 (CCL28)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

CCL28

Purity

>85% (SDS-PAGE)

Target Names

CCL28

Uniprot NO.

Q68A91

Species

Canis lupus familiaris (Dog) (Canis familiaris)

Source

Yeast

Expression Region

25-128

Target Protein Sequence

ILPIAS SCCTEVSHHI SRRLLERVNI CRIQRADGDC DLAAVILHVR RRRLCVSPHS HVIKQWMKEQ AAKKNTKGNI CHKKQAGKRK SKGAHQEKPE IHSHKSPY
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner.

Gene References into Functions

Inflammatory cytokines are important inducing factors for the production of CCL28 in the lesional skin of dogs with atopic dermatitis. atopic dermatitis. PMID:20022349
It was found that mRNA expression levels of CCL27 and CCL28 among the chemokines were significantly different between lesional and non-lesional skin in dogs with atopic dermatitis. PMID:18250572

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Subcellular Location

Secreted.

Protein Families

Intercrine beta (chemokine CC) family

Database Links

UNIGENE: Cfa.15807

KEGG: cfa:448795

STRING: 9615.ENSCAFP00000031374

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