Recombinant Dog Angiopoietin-2 (ANGPT2)

Baculovirus

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

ANGPT2

Uniprot NO.

A0A8J8

Alternative Names

ANGPT2Angiopoietin-2; ANG-2

Species

Canis lupus familiaris (Dog) (Canis familiaris)

Source

Yeast

Expression Region

19-495

Target Protein Sequence

YN NFRRSMDSIG RRQYQVQHGS CSYTFLLPET DNCRSPGSYV PNAVQRDAPL DYDDSVQRLQ VLENIMENNT QWLIKLENYI QDNMKKEMVE MQQNAVQNQT AVMIEIGTNL LNQTAEQTRK LTDVEAQVLN QTTRLELQLL EHSLSTNKLE KQILDQTSEI NKLQDKNSFL EKKVLDMEDK HIVQLRSIKE EKDQLQVLVS KQNSIIEELE KQLVTATVNN SVLQKQQHDL METVHSLLTM ISPSKSPKDT FVAKEEQIIY RDCAEVFKSG LTTNGIYTLT FPNSTEEIKA YCDMETSGGG WTVIQRREDG SVDFQRTWKE YKVGFGNPSG EHWLGNEFVF QVTNQQPYVL KIHLKDWEGN EAYSLYEHFY LSGEELNYRI HLKGLTGTAG KISSISQPGN DFSTKDADND KCICKCSQML TGGWWFDACG PSNLNGMYYP QRQNTNKFNG IKWYYWKGSG YSLKGTTMMI RPADF
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating angiogenic signals mediated by ANGPT1. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

Subcellular Location

Secreted.

Database Links

UNIGENE: Cfa.13296

KEGG: cfa:607616

STRING: 9615.ENSCAFP00000012670

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