Home
Product
Protein
Recombinant Proteins
Recombinant Dog AT-rich interactive domain-containing protein 5B (ARID5B), partial

Recombinant Dog AT-rich interactive domain-containing protein 5B (ARID5B), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

ARID5B

Uniprot NO.

E2R9X2

Alternative Names

ARID5BAT-rich interactive domain-containing protein 5B; ARID domain-containing protein 5B

Species

Canis lupus familiaris (Dog) (Canis familiaris)

Source

Yeast

Expression Region

1-1187

Target Protein Sequence

MEPNSLQWVG SPCGLHGPYI FYKAFQFHLE GKPRILSLGD FFFVRCTPKD PICIAELQLL WEERTSRQLL SSSKLYFLPE DTPQGRNSDH GEDEVIAVSE KVIVKLEDLV KWVHSDFSKW RCGLQAGAVK TTALGRNGQK EALLKYRQST LNSGLNFKDV LKEKADLGED EEETNVIVLS YPQYCRYRSM LKRIQDKPPS ILTDQFALAL GGIAVVSKNP QILYCRDTFD HPTLIENESI CDEFAPNLKG RPRKKKPCPQ RRDSFSGVKD SNNNSDGKAV AKVKCEARSA LSKPKNNHNN CKKVSNEEKP KVAIGEECRA DEQAFLVALY KYMKERKTPI ERIPYLGFKQ INLWTMFQAA QKLGGYETIT ARRQWKHIYD ELGGNPGSTS AATCTRRHYE RLILPYERFI KGEEDKPLPP IKPRKQENSS QENENKTKVS GTKRIKHEIP KSKKEKENAP KPQESPEVSS EPEKEQETSN QKSITEPLPA AEGKRKMEGY QDFAARPVGS RADPEKDSDA DRGAGGATAA EEAGEQGPVP PLPSAPAAPD RGPALGPGAG KQPLTSPSAP ADSKQEPQPC CFAESPDSEP QEPPFPGFPA AQPPLASQSE LEEDKLPAMA DYIANCTVKV DQLGSDDIHN ALKQTPKVLV VQSFDMFKDK DLTGPMNENH GLNYTPLLYS RGNPGIMSPL AKKKLLSQVS GAGLSGSYPY GSPPPLISKK KLIPRDELCS GLPQAHPGQG SDHAAVSRPS VIQHVQSFRS KASEERKGLG DLFKHDKLGR SEPHRCSFSK HHLGPLADSY ALKPDAPEGK DKLLEKRALP HAHVPSFLAD FYSSPHLHSL YRHAEHHLHA EQTSKYACRD AYRESENSSF PAHKHQEKLH VNYLASLHLQ DKKPAPAEAP ADEQPTDLSL PKNLHKPTGK VLGLAHAAPG PQESKGAPQF PAGNGQSRDG HPKACRVSPM TLSAPKKYPE PLSRASRPHH VRLESFRKLE GMVHPVLHRK AGPQAVGAAR PIKRGLEDLD LVIAGKKARA VSPLDPPKEA CGKDKGAELE GEGGKAAAAH GGPAADGHKA ALSSPIFPGL YSGSLCGSGL GSRLPAGYSH SLQYLKNQTV LSPLMQPLAF HSLVMQRGIF TSPTNSQQLY RHLAAATPVG SSYGDLLHNS IYPLAAINPQ AAFPASQLSS VHPSTKL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

Submit a Review here

Target Background

Function(From Uniprot)

Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Acts by forming a complex with phosphorylated PHF2, which mediates demethylation at Lys-337, leading to target the PHF2-ARID5B complex to target promoters, where PHF2 mediates demethylation of dimethylated 'Lys-9' of histone H3 (H3K9me2), followed by transcription activation of target genes. The PHF2-ARID5B complex acts as a coactivator of HNF4A in liver. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes. Overexpression leads to induction of smooth muscle marker genes, suggesting that it may also act as a regulator of smooth muscle cell differentiation and proliferation.

Subcellular Location

Nucleus.

Protein Families

ARID5B family

Database Links

STRING: 9615.ENSCAFP00000037005

Promotions