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Recombinant Dog AP-3 complex subunit beta-1 (AP3B1), partial

Recombinant Dog AP-3 complex subunit beta-1 (AP3B1), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Abbreviation

AP3B1

Purity

>85% (SDS-PAGE)

Target Names

AP3B1

Uniprot NO.

Q7YRF1

Alternative Names

AP3B1; ADTB3AAP-3 complex subunit beta-1; Adaptor protein complex AP-3 subunit beta-1; Adaptor-related protein complex 3 subunit beta-1; Beta-3A-adaptin; Clathrin assembly protein complex 3 beta-1 large chain

Species

Canis lupus familiaris (Dog) (Canis familiaris)

Source

Yeast

Expression Region

1-1091

Target Protein Sequence

MSGNSFAYSE QAGGGEATEL GQEATSTVSP SGAFGLFSSD LKKNEDLKQM LESNKDSAKL DAMKRIVGMI AKGKNASELF PAVVKNVASK NIEIKKLVYV YLVRYAEEQQ DLALLSISTF QRALKDPNQL IRASALRVLS SIRVPIIVPI MMLAIKEASA DLSPYVRKNA AHAIQKLYSL DPEQKEMLIE VIEKLLKDKS TLVAGSVVMA FEEVCPDRID LIHKNYRKLC NLLVDVEEWG QVVIIHMLTR YARTQFVSPW KEDDGLEDNE KNFYESDDEQ KEKTDQKKKP YAMDPDHRLL IRNTKPLLQS RNAAVVMAVA QLYWHISPKS EVGIISKSLV RLLRSNREVQ YIVLQNIATM SIQRKGMLEP YLKSFYVRST DPTMIKILKL EILTNLANEA NISTLLREFQ TYVKSQDKQF AAATIQTIGR CATSISEVTD TCLSGLVCLL SNRDEIVVAE SVVVIKKLLQ MQPAQHGEII KHMAKLLDSI TVPVARASIL WLIGENCERV PKIAPDVLRK MAKSFTNEDD LVKLQILNLG AKLYLTNSKQ TKLLTQYILN LGKYDQNYDI RDRTRFIRQL IVPNEKSGAL SKYAKKIFLA QKPAPLLESP FKDRDHFQLG TLSHTLNTKA IGYLELSNWP EVAPDPSVRN VEVIELQAKE WTPAGKAKKE NPARKFYSDS EEEEDSSDSS SDSESESGSA SGEQDEEGDS SEDSSEDSSS EHRSDSESVS EVGDKRTAKR NSKSKGKSDS EDEEKENEKS KTSDSSSTDS SSVEESSSDS ESESESESES ESKKVTMEKE KKTKEDRNLT KDVSLLDLDD FNPVSTPVVL PTPALSPSLI ADLEGLNLST SSSVISVNTP VFVPVKTHVL LHRMSGRGLA AHYFFPRQPC IFGDKMVSIQ ITLNNTTDRK IENIHIEGKK LPMGMQMHVF NPIESLEPEG SITVSMGIDF CDSTQTASFQ LCTKDDCFNV NIQPPVGELL LPVAMSEKDF KKEQGMLTGM NETSTVIIAA PQNFTPSVIL QKVVNIANVG VVPSGQDNIY RFAAKTVHSG SLMLVTVELK EGSTAQLIIN TERTVIGSVL LRELKPVLSQ G
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

Subcellular Location

Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus.

Protein Families

Adaptor complexes large subunit family

Database Links

UNIGENE: Cfa.169

KEGG: cfa:403459

STRING: 9615.ENSCAFP00000013540

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