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Recombinant Dictyostelium discoideum DNA repair protein RAD50 (rad50), partial

Recombinant Dictyostelium discoideum DNA repair protein RAD50 (rad50), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

rad50

Purity

>85% (SDS-PAGE)

Target Names

rad50

Uniprot NO.

Q54CS9

Alternative Names

rad50; DDB_G0292786; DNA repair protein RAD50; EC 3.6.-.-; DNA recombination/repair protein

Species

Dictyostelium discoideum (Slime mold)

Source

Yeast

Expression Region

1-1351

Target Protein Sequence

MTSIEKLLVQ GIRSFDPREA SVIDFYSPLT LIVGQNGAGK TTIIECLKYT CTGEMPPNCS SGQAFIHDTK IAGESEVKAQ IKLRFKNPIG KPIVASRSLS LIQKSNKKQE YKQIDASLQS YTSDGQKVSK SFRCSDMDKE IPDLMGVAKP ILKHVIFCHQ EDSNWPLSES AKLKLKFDEI FSAVKYTKAL KSLKDKRKEL TTLIKELKLR LETISANIEH CNRIRKELIK AEEIYSNGNK SLEDIKIAII EKQKTLSTIK IAESKLQELK NEVTVLNARK LEMERVKNQL FNSLTEVYQN ETDEELVFMQ SEFNRECETM ATAEKELLEN SEVLLSQKEV INNLIKENSS QKGRLQSLIS QQDSILSDRD KQMKELVTRY KMSDFIQIQL PYQKEIVIKF INEITQKFDT LTSGISNYSK TNKQKLNAIQ MKINQKRVDS NQFTSSSNEK MSTITLNSKK IQSLDQEIQQ HTNSIGEIDT LEKQIQFSQS ELSILKSDAN LQEIQQSLDN LTTEKLEIEK EIQSLQSSLK LLNLQASSRT RLNIKRKEIQ QNQQNINSQL NSQIINSINL ILPNEFNNDN NNDDDDDQFR FNIIQRIEPI VPLINKKRLI FTNQLNELKQ QFQILQNKKN QIDAQLTSSI EPQLKKKQIE LESYEKLIND SKLKQSNLFE NVNSNNNNNN NNNNGITVLL FENKINEMKL SLEKLEKSFI VLESEDILYK EYIEKANQDK ECSLCKNEMN GNELTSFVHT LETHCNDIPN QLKQLKIEIS NSKIQLEKFN KLLPIIVKRE ELIEKSIPEL KESQKNLLEQ QLKSNEMVLE KQNQIESLES QSVLYQQVTL VFQYIDQTKQ SIQSIESEIQ KEEKEIMKQS SDLRTIEEVD KDLEIQQEQL KTIEKEISNF TNKQKNDQIG IFEKERQLIS IKNQLTTIKS ASGIIDHLRD TKKELQSNNQ QLQLEIENLQ QSIDQSNNDA KQLENEFQQL EIEFEKKIDA YSKEKNTFSV RLDSINSLQS KILDPSELCK QLNEIQEKNQ ELESNLSTLS QDYLIGQQHI STIQQNLSSK DITKRAISDN ISFRQHKNNV EQIIRQISRK NELIKEMMQS QLEIDSNKLE QEINSLKSKF DQITGQTAVL QSQINSNRQE LSKPTYKNID DVNKDLLIKL QTTETVGKDL DKYYKALDKS LMKYHTLKMD EINRSIKEIW QTTYKGSDID TIEIRSEESG TANKTINYRV VMIKGDVELD MRGRCSAGQK VLACLVIRLA LAENFCSNCG ILALDEPTSH LDRANIESFA NSLLNIIESR KSQKGFQLII ITHDEEFVQY LSRGNYCDYY WRVTKNANQH SHLERKEIAE L
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Essential component of the MRN complex, a complex that possesses single-stranded DNA endonuclease and 3' to 5' exonuclease activities, and plays a central role in double-strand break (DSB) repair, chromosome morphogenesis, DNA repair and meiosis. In the complex, it mediates the ATP-binding and is probably required to bind DNA ends and hold them in close proximity.

Subcellular Location

Nucleus. Chromosome, telomere.

Protein Families

SMC family, RAD50 subfamily

Database Links

KEGG: ddi:DDB_G0292786

STRING: 44689.DDB0232401

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