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Recombinant Devario aequipinnatus Sonic hedgehog protein (shh)

Recombinant Devario aequipinnatus Sonic hedgehog protein (shh)

Code
MSDS	MSDS
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

shh

Uniprot NO.

O13234

Species

Devario aequipinnatus (Giant danio) (Danio aequipinnatus)

Source

Yeast

Expression Region

1-121

Target Protein Sequence

YGRRRHPKKL TPLAYKQFIP NVAEKTLGAS GRYEGKITRN SERFKELTPN YNPDIIFKDE ENTVMNHWPG VKLRVTEGWD EDGHHFEESL HYEGRAVDIT TSDRDKSKYG TLSRLAVEAG F

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Description

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Target Background

Function

Intercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning, dorso-ventral patterning of the brain and early patterning of the developing eyes. Displays floor plate-inducing activity. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO.

Subcellular Location

Secreted. Cell membrane.

Protein Families

Hedgehog family

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