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Recombinant Danio rerio Ras-related protein Rap-1b (rap1b)

Recombinant Danio rerio Ras-related protein Rap-1b (rap1b)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Abbreviation

rap1b

Purity

>85% (SDS-PAGE)

Target Names

rap1b

Uniprot NO.

Q6TEN1

Alternative Names

rap1b; si:dkey-31f5.4; Ras-related protein Rap-1b

Species

Danio rerio (Zebrafish) (Brachydanio rerio)

Source

Yeast

Expression Region

1-181

Target Protein Sequence

MREYKLVVLG SGGVGKSALT VQFVQGIFVE KYDPTIEDSY RKQVEVDGQQ CMLEILDTAG TEQFTAMRDL YMKNGQGFAL VYSITAQSTF NDLQDLREQI LRVKDTDDVP MILVGNKCDL EDERVVGKEQ GQNLARQWNS CAFLESSAKS KINVNEIFYD LVRQINRKTP VTGKPRKKST C
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Probable GTP-binding protein that possesses GTPase activity. May play a role in endothelial cell polarity and endothelial barrier function.

Gene References into Functions

Rap1b activates Integrin/Fibronectin receptors as part of an "inside-out" signaling pathway that promotes Integrin binding to FN, FN matrix assembly, and subsequent stabilization of morphological somite boundaries. PMID:23192979
Using 2 distinct pharmacologic VEGFR2 inhibitors the study shows that rap1b and VEGFR2 act additively to control angiogenesis in vivo. PMID:21636859

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Subcellular Location

Cell membrane. Cytoplasm, cytosol. Cell junction.

Protein Families

Small GTPase superfamily, Ras family

Database Links

UNIGENE: Dr.76648

KEGG: dre:321107

STRING: 7955.ENSDARP00000114387

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