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Recombinant Danio rerio Presenilin-2 (psen2), partial

Recombinant Danio rerio Presenilin-2 (psen2), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details

Abbreviation

psen2

Purity

>85% (SDS-PAGE)

Target Names

psen2

Uniprot NO.

Q90ZE4

Alternative Names

psen2; Presenilin-2; PS-2; Zf-PS2; EC 3.4.23.-; Pre2

Species

Danio rerio (Zebrafish) (Brachydanio rerio)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.

Gene References into Functions

Zebrafish pre2 is maternally and ubiquitously expressed during early embryo development, whereas Pre2 protein expression is initiated between 6 and 12 hours post fertilisation (hpf), suggesting strict regulation of pre2 translation. PMID:12424519
These results suggest that Psen2 plays a more prominent role in Notch signalling and embryo development in zebrafish than in mammals, and that the effect of reduced Psen2 can be ameliorated by Psen1 loss. PMID:19563801

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Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.

Protein Families

Peptidase A22A family

Database Links

UNIGENE: Dr.81267

KEGG: dre:58026

STRING: 7955.ENSDARP00000011791

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