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Recombinant Danio rerio Optineurin (optn), partial

Recombinant Danio rerio Optineurin (optn), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

optn

Purity

>85% (SDS-PAGE)

Target Names

optn

Uniprot NO.

Q5RI56

Species

Danio rerio (Zebrafish) (Brachydanio rerio)

Source

Yeast

Expression Region

1-517

Target Protein Sequence

MNGDISHPRG SGPGNLGSLE ETLQQMNTLI KENRDLKEAL KQTNLSMKER FEGLSAWKEK QKEERDFLEQ RLEEARTRLN TMDVENEALK NQVKELEKSG AECLHTELEA LRGQILRIQA EKNDLVAMNS ELQLKMGQGS PSNSFIEIRI ADDDLKVTKD LSSVPEASAF SMPKAESEEQ TVRQLLRSLR AETDEKERLQ LTLQEARGRI AELESKLEHA DSSAQTSLPS AAETNASTEV KNLEDQLLKL CNELKQAQIK LDEAESMKRN LQDRCKDLEQ DLGTLKTQLG DKQKVQAEND CLKVQMESLQ AAIKLEQKKT QDEKNNLNQL KDAYTKLFED YSELQEEKKK RESCVSKDDY DELQTRFATA EKALADKQQK IDEMKMELFQ KEKDLETISV FQAQAEIYSS DFYAERAARE KIHEEKERLA TQLEYVKKQN SQLQEEMESL GRHSMSEMQR RHVPRGANPQ GPTAPNNLPG GRGEWQQQNI PDHACPKCGE VLPDLDSLQI HIMDCII
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Probably part of the TNF-alpha signaling pathway that can shift the equilibrium toward induction of cell death. May act by regulating membrane trafficking and cellular morphogenesis.

Gene References into Functions

Loss of optineurin in vivo results in elevated cell death and alters axonal trafficking dynamics PMID:25329564

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Subcellular Location

Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle. Recycling endosome. Cytoplasmic vesicle, autophagosome.

Database Links

UNIGENE: Dr.79390

KEGG: dre:336159

STRING: 7955.ENSDARP00000099052

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