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Recombinant Danio rerio Myeloid differentiation primary response protein MyD88 (myd88)

Recombinant Danio rerio Myeloid differentiation primary response protein MyD88 (myd88)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Abbreviation

myd88

Purity

>85% (SDS-PAGE)

Target Names

myd88

Uniprot NO.

Q5XJ85

Alternative Names

myd88; Myeloid differentiation primary response protein MyD88

Species

Danio rerio (Zebrafish) (Brachydanio rerio)

Source

Yeast

Expression Region

1-284

Target Protein Sequence

MASKLSIDHE AIPVTALNCS FRKKLGLFLN PTNTVAADWR TVAELMDFTY LEIKNFEKRD CPFEKVLTDW ETRPDATVAN LLSILEKAER KDVISELKEI LDDDCRKYME RQQRKPLQVP VVDSCGPRTQ EREGITLYDD PQGLTPETFD AFICYCQSDI QFVHEMIKQL EHTEYNLKLC VFDRDVLPGT CVWTIASELI EKRCKRMVVV ISDDYLDSDA CDFQTKFALS LCPGARTKRL IPVVYKSMKR PFPSILRFLT ICDYSKPCTQ VWFWTRLAKA LSLP
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response.

Gene References into Functions

microbiota-induced, Myd88-dependent signaling inhibits host Notch signaling in the intestinal epithelium, thereby promoting secretory cell fate determination PMID:29475973
DrIRF1 works in concert with MyD88 to activate zebrafish IFNvarphi3 but not IFNvarphi1. These results provide insights into the evolving function of IRF1 as a positive IFN regulator. PMID:25535281
MyD88 signaling has an important protective role during early pathogenesis. PMID:23471913
MyD88-dependent signaling is involved in the innate immune response of the developing zebrafish embryo, a model for the study of vertebrate innate immunity. PMID:16552074