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Recombinant Danio rerio Mediator of RNA polymerase II transcription subunit 12 (med12), partial

Recombinant Danio rerio Mediator of RNA polymerase II transcription subunit 12 (med12), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

med12

Purity

>85% (SDS-PAGE)

Target Names

med12

Uniprot NO.

Q2QCI8

Species

Danio rerio (Zebrafish) (Brachydanio rerio)

Source

Yeast

Expression Region

1-2173

Target Protein Sequence

MAAFGVLSYE HRPLKRPRLG PPDVYPQDPK QKEDELTALN VKQGFNNQPA VSGDEHGSAK NVNFNSSKIS SNFSSIIAEK LRCNTFPDTG KRKPQVNQKD NFWLVTARSQ SSINNWFTDL AGTKPLTQLA KKVPIFSKKE EVFGYLAKYS VPVMRSAWMI KMTCAYHAAI TENKMKKRHV IDPCIEWTPI ITKYLWEQLQ KVAEFYRQSP SQGCGSPLPA PPAEVETAMK QWEYNEKLAM FMFQDGMLDR HEFLTWVLEC FEKIRPGEDE LLRLLLPLLL QYSGEFVQSA YLSRRLAYFC TRRLNLLLSD GSIGPGPGGH QAHGISAQQG NALPPTPTSQ PAGGNQPQTP FTDFYICPQH RPVVFGLSCM LQSIVLCCPS ALVWHYSLTD SRNKTGSPLD LLPIAPSNLP MPGGNSTFNQ QVRAKVREIE EQIKERGQAV EFRWSFDKCQ ETTAGFTISR VLHTLEVLDN HSFEKSDFSN SLDSLYNRIF GSGQSKDGHE MSPDDDAVVT LLCEWAVSCK RSGPHRAMVV AKLLEKRQTE IEAERCGESE VVDEKGSVSS GSLSAATLPV FQDVLLQFLD TQAPVLTEPG NESERVEFSN LVLLFYELIR HDVFSHNIYM CTLISRGDLA SNSHLPRPRS PSDEPSDESE RKDQDAGSSV KMEDTGMSES MEIDHNSSAN FDEMFSPPMH CESKGSPSPE KQAQEQESKS TAKDKGMDPA FPLVYEQPRH IQYATHFPIP QEESASHECN QRLVVLYGVG KQRDEARHAI KKITKDILKV LNRKSTAETG GEEGQKRKRS KPEAFPTAED IFSKFQHLSH FDQHQVTSQV SRNVLEQITS FALGMSYHLP LVQHIQFIFD LMEYSLNISG LIDFAIQLLN ELSLVEAELL LKSSNLAGSY TTGLCLCIVA VLRRYHSCLI LNPDQTAQVF DGLRIVVKSG VNPADCSSAE RCILAYLYDL YTSCSHLKSK FGEIFSEFCS KVKNSIYYNI DPSDSNMLWD QMFMIDAITN PTAHNLNHSM LGKITNELND SPANRYSFVC NVLMDVCVDH RDPERVNDIG ILCAELTAYC RSLSAEWLGV LKALCCSSNN GNCGFNDLLC NVDVSDLSFH DSLATFVAIL IARQCLLLED LVRCVAIPSL LNAACSEQDS EPGARLTCRI LLHLFRTPQR NPCPQDGTKS DKSIVGIRSS CDRHLLAASQ NSIVVGAVFA VLKAVFMLGD AELKGSGFSH PAGLDDIGED DMGSKKSGGR NVSIETASLV VYAKYVLKSI CHQEWVGERC LKSLSEDSSA LQDPVLVNIQ AQRLLQLICY PHRQLDSEEG DNPQRQRIKR ILQNMDQWTM RQSSLELQLM IKQSSNNELY SLLENIAKAT IEVFQKSAEM NSSNPSWNGS AVSGSSVSNS NSASKLKPVL SSSERSGVWL VAPLIGKLPT SVQGHVLKAA GEELEKGQHL GPSSRKERDR QKQKSMSLLS QQPFLSLVLT CLKGQDEQRE GLLTSLYSQV QQIVTNWRED QYQDDCKAKQ MMHEALKLRL NLVGGMFDTV QRSTQQTTEW AVLLLDIISS GTVDMQSNNE LFTTVLDMLS VLINGTLAAD MSSISQGSME ENKRAYMNLV KKLRKELGDR QSESLEKVRQ LLPLPKQTRD VITCEPQGSL IDTKGNKIAG FEKEGLQVST KQKISPWDVF EGLKHSAPLS WGWFGTIRVD RKVTKFEEQQ RLLLYHTHIK PKQRSYYLAP LNLPQEEEEP LTPVPPEPDK KLDTAKVEKS VSNVPTKKKK KKPASTVKQE DYKPHNTVMQ YAPGMTPDLP LSMGQTNMSY RMGYQAPMNM YAQNQPLPPG GPGLEPPFRP RVPMNKMPPR PNYTMPNMQT AGMGNLMGME KQYQMNYKPM PNMAQGQMLR HQLQGHNHLI GQQIRQVTPN PQYSSMQPAQ NIPQGYTSYG SHMGMQPHPS QTPGMVPNSY GNQGFQTGHP ATNPTMVDSI RQMQQRPGYV HQQAPAAYGH TIQSTQRFPH QSMQQTPMMH GLAQSHLGVQ GIHPNMRPNQ MMEQQQQQQQ QQQQQQQQQQ QVHQQQQHIR QGPVFRPQQQ QQVQQQVQQQ VQQQQVQQQQ VQQQVQPQQV QQQQVQQQQQ QQVSAAQPPA QALGMQALPP QQPMFQRQGM QQTQQQQQTA ALVRQLQQQL SSTQPAQNNS SYY
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for development of the body axis, brain, ear, kidney, forelimb and neural crest and for pigmentation. Acts as a coactivator for sox9a and/or sox9b promoting the expression of several neuronal determination genes.

Subcellular Location

Nucleus.

Protein Families

Mediator complex subunit 12 family

Database Links

UNIGENE: Dr.41439

STRING: 7955.ENSDARP00000124576

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