Recombinant Danio rerio Lysine-specific demethylase 7B (jhdm1db), partial

Code
MSDS
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Source
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
jhdm1db
Uniprot NO.
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Source
Yeast
Expression Region
1-577
Target Protein Sequence
MATAQLYCVC RQPYDVSRFM IECDICKDWF HGSCVEVEEH YAVDIDVYHC PNCDVHHGPS LMKKRRNWHR HDYTEPDDGS KPVQAGTSVF VRELQARTFP SGDEILQPMH GGQVTQRYLE RHGFRYPIIV SKREELGLRL PPPDFSIKDV ERYVGGNKVI DVIDVARQAD SKMKLKAFVK YYYSPQRPKV LNVISLEFSD TKMAELVVVP DIAQKMSWVE NYWPDDSYFP KPFVQKYCLM GVKDSYTDFH IDFGGTSVWY HVLWGEKIFY LIKPTPANLA LYEEWSSSPN QSEVFFGEKV DKCYKCVVRQ GTTLLIPTGW IHAVLTSQDC MAFGGNFLHN LNIGMQLRCY EMERRLKTPD LFKFPYFEAI CWYVAKNLLE TLKESREENC LPPEYLIKGV KALITALRNW LKREVTEPAS EVPDHIRPNH LIKMLTKEIQ YLENGNCGNK PMKLQESSIC PSTRSAHERG SHARKTARRL RGHHHHHHRH HHHHHHHHHH NHQHSDGPKA PSHLDIYEQH TQEVLKRLEM GPYEEDASFN LKVNGKFNKV STASAAAAER SLENDLRLVL CNGQIVR
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
Storage
The shelf life of liquid-form form is 6 months around at -20°C/-80°C.
The shelf life of lyophilized form is 12 months around at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Description

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Target Background

Function
Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code.
Subcellular Location
Nucleus.
Protein Families
JHDM1 histone demethylase family, JHDM1D subfamily
Tissue Specificity
Predominantly expressed in brain.
Database Links
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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