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Recombinant Danio rerio Glial cell line-derived neurotrophic factor (gdnf)

Recombinant Danio rerio Glial cell line-derived neurotrophic factor (gdnf)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

gdnf

Purity

>85% (SDS-PAGE)

Target Names

gdnf

Uniprot NO.

Q98TU0

Alternative Names

gdnfGlial cell line-derived neurotrophic factor; zGDNF

Species

Danio rerio (Zebrafish) (Brachydanio rerio)

Source

Yeast

Expression Region

90-235

Target Protein Sequence

S SDVEPQMKRD RVRQKAAANT EKSGGRGRGE RKRSRGRARS RDDRVKGQGR GCLLKEIHLN VTDLDLGYRT KEELIFRYCS GPCHDAETNY DKILNNLTHN KKLDKDTPSR TCCRPIAFDD DISFLDDSLE YHTLKKHSAK KCACV
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. Essential for the development of the enteric nervous system, but appears dispensable for the development of the kidney and primary motor neuron.

Subcellular Location

Secreted.

Protein Families

TGF-beta family, GDNF subfamily

Tissue Specificity

First expressed at 14 hours post-fertilization (hpf) in the ventral half of anterior somites and in intermediate mesoderm. Ventral somitic expression persists and extends more posteriorly over the next 12 hours. Expressed throughout the ventral trunk meso

Database Links

UNIGENE: Dr.11721

STRING: 7955.ENSDARP00000124666

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