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Recombinant Danio rerio Estrogen receptor (esr1), partial

Recombinant Danio rerio Estrogen receptor (esr1), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

esr1

Uniprot NO.

P57717

Alternative Names

esr1; esr; nr3a1Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1

Species

Danio rerio (Zebrafish) (Brachydanio rerio)

Source

Yeast

Expression Region

1-569

Target Protein Sequence

MYPKEEHSAG GISSSVNYLD GAYEYPNPTQ TFGTSSPAEP ASVGYYPAPP DPHEEHLQTL GGGSSSPLMF APSSPQLSPY LSHHGGHHTT PHQVSYYLDS SSSTVYRSSV VSSQQAAVGL CEELCSATDR QELYTGSRAA GGFDSGKETR FCAVCSDYAS GYHYGVWSCE GCKAFFKRSI QGHNDYVCPA TNQCTIDRNR RKSCQACRLR KCYEVGMMKG GIRKDRGGRS VRRERRRSSN EDRDKSSSDQ CSRAGVRTTG PQDKRKKRSG GVVSTLCMSP DQVLLLLLGA EPPAVCSRQK HSRPYTEITM MSLLTNMADK ELVHMIAWAK KVPGFQDLSL HDQVQLLESS WLEVLMIGLI WRSIHSPGKL IFAQDLILDR SEGECVEGMA EIFDMLLATV ARFRSLKLKL EEFVCLKAII LINSGAFSFC SSPVEPLMDN FMVQCMLDNI TDALIYCISK SGASLQLQSR RQAQLLLLLS HIRHMSNKGM EHLYRMKCKN RVPLYDLLLE MLDAQRFQSS GKVQRVWSQS EKNPPSTPTT SSSSSNNSPR GGAAAIQSNG ACHSHSPDP
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

Gene References into Functions

Comprehensive genetic analysis for differential functions of esr1, esr2a, and esr2b in fish reproduction. PMID:28398516
This study revealed similar patterns of transcript abundance across reproductive morphs for ERbeta1, ERbeta2, ERalpha, and aromatase in the forebrain and saccule. PMID:23460422
It was concluded that morpholino (MO) oligonucleotid technology in zebrafish embryos is an good approach for investigating the interplay of estrogen receptor subtypes in a true physiological context. PMID:23928376
Report stable reporter gene assays based on stable expression of subtypes of zebrafish ER (zfERalpha, zfERbeta1, and zfERbeta2) coupled to estrogen response element-driven luciferase in a zebrafish liver cell line. PMID:22045033
during embryogenesis two of the three 17beta-estradiol receptor genes, esr1 and esr2b are expressed, and in presence of ligand the mRNA levels of these two genes increase PMID:20300630
Data show that temperature and photoperiod significantly influence the transcription of the estrogen-responsive genes, Vtg1, Vtg2, ER alpha and ER beta after a 21-day exposure to endocrine-disrupting chemicals. PMID:19931644
Cloning of the cDNAs corresponding to three oestrogen receptors (esr1, ERalpha; esr2b, ERbeta1; and esr2a, ERbeta2 ). PMID:12063182
Data show that the hepatic expression of estrogen receptor alpha, beta1 and beta2 genes responds differently to estradiol. PMID:15171726
genistein binds and activates the three zebrafish estrogen receptors ERalpha, ERbeta-A and ERbeta-B and induces apoptosis in an ER-independent manner PMID:19319186