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Recombinant Danio rerio Dual specificity mitogen-activated protein kinase kinase 6 (map2k6)

Recombinant Danio rerio Dual specificity mitogen-activated protein kinase kinase 6 (map2k6)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

map2k6

Purity

>85% (SDS-PAGE)

Target Names

map2k6

Uniprot NO.

Q9DGE0

Alternative Names

map2k6; map2k3; Dual specificity mitogen-activated protein kinase kinase 6; MAP kinase kinase 6; MAPKK 6; EC 2.7.12.2; Mitogen-activated protein kinase kinase 3; zMKK3

Species

Danio rerio (Zebrafish) (Brachydanio rerio)

Source

Yeast

Expression Region

1-361

Target Protein Sequence

MEGGSDKESK VFCDSPSPNP KGEMSVPSNV RGKKKLPKEL KLPKEVFEKP APAPTPPRDL DSKAYVTIGE KNFVVKADDL EQIGELGRGA YGVVDKMRHV PSGVIMAVKR IRATVNTQEQ KRLLMDLDIS MRTVDCFYTV TFYGALFREG DVWICMELMD TSLDKFYKQV HEKGKTIPED ILGKITVSIV KALEHLHSNL SVIHRDVKPS NVLINMQGQV KMCDFGISGY LVDSVAKTMD AGCKPYMAPE RINPETNQKG YNVKSDIWSL GITMIELAIL RFPYDSWGTP FQQLKQVVEE PSPQLPADRF SADFVDFTSQ CLRKNSTERP TYTELMQHPF FTLHDSKDTD VASFVKTILG D
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 and plays an important role in the regulation of cellular responses to cytokines and all kinds of stresses. The p38 MAP kinase signal transduction pathway leads to direct activation of transcription factors. Phosphorylation by MAP2K6 asymmetrically activates p38 on one side of the blastodisc, an event which is necessary for blastomere cleavage.

Subcellular Location

Nucleus. Cytoplasm. Cytoplasm, cytoskeleton.

Protein Families

Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily

Database Links

UNIGENE: Dr.150491

KEGG: dre:65239

STRING: 7955.ENSDARP00000111296

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