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Recombinant Danio rerio DNA damage-inducible transcript 4 protein (ddit4)

Recombinant Danio rerio DNA damage-inducible transcript 4 protein (ddit4)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

ddit4

Purity

>85% (SDS-PAGE)

Target Names

ddit4

Uniprot NO.

Q7T346

Alternative Names

ddit4; zgc:64114DNA damage-inducible transcript 4 protein

Species

Danio rerio (Zebrafish) (Brachydanio rerio)

Source

Yeast

Expression Region

1-220

Target Protein Sequence

MQDQLISSLS SEDSSPSTPT SDAPAKRLSW SKLMQKLHSS QSLDSDSDNH SSTDDSSDSG SICIPDVSQS EFFDPTEEAL CKEVVQLIAL NLTDAKDGVL HCSKLLIPEK LLEHIGQELV HLSVSEPCGL RGALIDLCVE QDGSCHAAAQ IAVDPYLVPT FQLTLVLRLD SRGLWPKIQG LFTGRSPASP AVRRALRLST GFRAIKRKLY SSEELLIEEC
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Regulates cell growth, proliferation and survival via inhibition of the activity of the mammalian target of rapamycin complex 1 (mTORC1). Inhibition of mTORC1 is mediated by a pathway that involves ddit4/redd1, akt1, the tsc1-tsc2 complex and the GTPase rheb. Plays an important role in responses to cellular energy levels and cellular stress, including responses to hypoxia and DNA damage, via its effect on mTORC1 activity. Plays a role in neuronal differentiation, neuron migration during embryonic brain development and in neuronal cell death.

Gene References into Functions