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Recombinant Danio rerio Apoptotic protease-activating factor 1 (apaf1), partial

Recombinant Danio rerio Apoptotic protease-activating factor 1 (apaf1), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Abbreviation

apaf1

Purity

>85% (SDS-PAGE)

Target Names

apaf1

Uniprot NO.

Q9I9H8

Alternative Names

apaf1Apoptotic protease-activating factor 1; APAF-1

Species

Danio rerio (Zebrafish) (Brachydanio rerio)

Source

Yeast

Expression Region

1-1261

Target Protein Sequence

MEERARSRLL RSKATLEQDI KASYLMDHMI SDGVLTNDEE AKVLSKATRK EQAVALLETL LRKDNRAYIS FYNALIRESY GDLASLLHSD LPLLSPEGEK SFADGVSPSV QAILSVGGVP QRPVVFVSRP PLLNLIREML YQLRDTPGWV TVFGMAGSGK SVMAAEVVRD RSLIKECFPD GVHWLSVGQC ERADLLVRMQ SLCFRLEQCQ SSDTSQRPPS TVEEAKERLR FLMLRRFPRS LLILDDVWDS SSLRSFDIQC RVLLTTRNRA LTDSVSGVRY EVPVENGLDE EKALEILALY VNGKMHKLPE QARSIVSECK GSPLVVSLIG ALLREFPDRW SYYLRQLQQK QFKRIRKSSS YDYEALDQAM DASLQVLEAE HQELYRDLSV MQKDIKVPAK VLSVLWGLEL EEVEDVLQEF VNKSLLFRDC NQRPYRYYLH DLQLDFLAEQ NRDQIAELHK KMVRQYQRFY SKRPPDSADK DSLYWYQFIP YHMAKAGLSK ELYSLMFSLD WVKEKARIMG SAHLINDYVE YGEILDKENS EVRVQFQEFL SLNGHHLEQR PFPDVVQLAL SQPDRSEVYR QALMQAQKRA SRGQIYLNWV NKNIEEGLSR LVMHPHQGAV YYACFSKDGS KIASCGASKA LRVFKSTSGE KLLELQAHEE DVLCCAFSPD DRHIATCASD RKVKLWNVER GVLIREFEVE HEEQINHCQF TNTGRRVLLA TCSNDKFTNT RLWNPNKKTS QNTMFGHMEP VNHCCFSPND LYLATSSSDG SLKLFEVSSA NEWKSIDVDS FFPESDEEIK AMVKCSTWSA DGSQIICAAR NTVFVFDVET SDLLLKLKTS RLSTIQFCHA CPNSSLLAVA LSHYTVELWN FESSKKKAEC SGHLSWVHCV QFSPDGSLLL SSSDDQTIRL WETDRVHTSS AVALKRDTDV LSSHSDATII APDSSNRLQV LSGSTGAVVL ESEELSSRIR CSCISRNAAF VALGSEDGTV QVIEVPSSKA SVKLSGHTKT VHHCQFTDDC EILITSSEDS TIRVWKWRTG ECMVLQGHME PVRKFHLLSS SSSPHLFSWS FDGTVKVWDL TRGQMLQDLV CHEGAVLSCD VSSDGRLFAT TSANRTAKVW SSASWKMLFL LEGHKDCVRS CRFSWDNKRL ATGDDNGEIR LWSMLDGALL KICPRDTKDS MNSYHAGWVT DLHFSPDNRV LVSTAGYIKW WSVESGEALQ TFYTMGGNLK KIHVSPDFST FITVDSIGIL YILKRLEGEG T
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.

Gene References into Functions

results provide evidence that Apaf-1 pharmacological inhibition has therapeutic potential for the treatment of apoptosis-related diseases. PMID:25330150

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Subcellular Location

Cytoplasm.

Database Links

UNIGENE: Dr.78833

KEGG: dre:58131

STRING: 7955.ENSDARP00000105810

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