Recombinant Cricetulus griseus Cadherin-2 (CDH2)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

CDH2

Uniprot NO.

O55075

Species

Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

Source

Yeast

Expression Region

1-238

Target Protein Sequence

TKPLDRELIA RFHLRAHAVD INGNRVENPI DIVINVIDMN DNRPEFLHQV WNGSVPEGSK PGTYVMTVTA IDADDPNALN GMLRYRILSQ APSTPSPNMF TINNETGDII TVAAGLDREK VQQYTLIIQA TDMEGNPTYG LSNTATAVIT VTDVNDNPPE FTAMTFYGEV PENRVEVIVA NLTVTDKDQP HTPAWNAVYR ISGGDPTGRF AIHTDPNSND GLVTVVKPID FETNRMFV
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Extracellular domain

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density.

Subcellular Location

Cell membrane; Single-pass type I membrane protein. Cell membrane, sarcolemma. Cell junction. Cell surface.

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