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Recombinant Coccidioides immitis Autophagy-related protein 13 (ATG13), partial

Recombinant Coccidioides immitis Autophagy-related protein 13 (ATG13), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

ATG13

Purity

>85% (SDS-PAGE)

Target Names

ATG13

Uniprot NO.

Q1E891

Species

Coccidioides immitis (strain RS) (Valley fever fungus)

Source

Yeast

Expression Region

1-980

Target Protein Sequence

MHQHRRTSSA VASPVSSPHP SSSRPITRDR GTARFGPNVS RGLGIDRQMD ASDQEQTIES PEKSPSQKLD QIIQNYHTKA ALVILHSRVD LSPATYHGVI RTNKWFNVEV NETEDLKDSL GVWKYSNCTD SRPPPLIIEV YLDLTQLTNN QSLVIIDDSG KRWDVVEALA TYGCLDNSRT SKSGVILERW RIDLGPGPDD LPLDMGSILP TVYKKSIVVF RSLYAYSKLL PAWKYSKRHS KIRPNPALSL KYRILQGPGG QIRSTNDPLT VPLHPGNGPV VDTYSFGVTD SPAGPLSALV TYRTNCDFRV DDSEALLSSR FMGVDERFFK PSLPSEDNFA AAGQEHGSLP VQKRDVGRPD LGQAYGSMST FHQVGATTGA SPISALRAAR ELAAGSPSSP TRPSHSPRPS QAGRVAALSG EGNHLIQRRP SISIQPFKAP PLSASPALVD SPVGSQPKNS APRVGPMDIT SSARQMPPPH GTPTTSRRSA HVSESAIASS TSGSPRPAPI SKYSSSFSHR RGRLSSGGAS KTDDDNNSSG RVSVSSSTVH PGSGTSADPA TTSSGSLQAD EDNISDFLKM LEMGKDLLSR KDSKSLDKNT KRTSAALSRF QKMRDSNAVL SDSMSSSLLL QPSSISSSKQ LPNAATSVAG ASISVSSSPG KAISPHTQHI PAVPSRLSSN SVVDYSHSHE DRHERRHRLS HESRRSPSEE RANDEPRLKR DESTANAIDI PTSPRPFIPS FRRSSSAAQR RSSPPVEDDL GDFLPFGMRS LSLGAEDRST LSLSELVRQQ ESSVPASDTN ALQQQNQKDT RTGQSIVDES PSRIDNVPGT SSPRQYQPRF AHGRGRGSFG HPQPHVSAAS SLGRASPIPN VTDADREGYI GSGNNGGTAV PPDTRRGSSH RFSFNRHLGT PANMDEDEPL LFAMSDFGAS RRSLEEGRKG ATTAGADHGG APSTELQPAA ETRSEGGPPS VSRGRYRAWP
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Activates the ATG1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy. Also involved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation. Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy. Finally, ATG13 is also required for glycogen storage during stationary phase.

Subcellular Location

Cytoplasm. Preautophagosomal structure.

Protein Families

ATG13 family, Fungi subfamily

Database Links

KEGG: cim:CIMG_01222

STRING: 246410.XP_001247451.1

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