Recombinant Chicken Yorkie homolog (YAP1)

Product Details

Purity
>85% (SDS-PAGE)
Target Names
YAP1
Uniprot NO.
Species
Gallus gallus (Chicken)
Source
Yeast
Expression Region
1-448
Target Protein Sequence
MDPGQPQPQQ PPQAAQPPAP QQAAPQPPGA GSGAPGGAAQ PPGAGPPPAG HQIVHVRGDS ETDLEALFNA VMNPKGANVP HTLPMRLRKL PDSFFKPPEP KAHSRQASTD AGTAGALTPQ HVRAHSSPAS LQLGAVSPGT LTPSGVVTGP GAPSSQHLRQ SSFEIPDDVP LPPGWEMAKT PSGQRYFLNH IDQTTTWQDP RKAMLSQMNV TAPTSPPVQQ NLMNSASAMN QRISQSAPVK QPPPLAPQSP QGGVMGGSSS NQQQQMRLQQ LQMEKERLRL KHQELLRQEL ALRSQLPTME QDGGSQNPVS SPGMSQELRT MTTNSSDPFL NSGTYHSRDE STDSGLSMSS YSVPRTPDDF LNSVDEMDTG DSISQSNIPS HQNRFPDYLE AIPGTNVDLG TLEGDGMNIE GEELMPSLQE ALSSDILNDM ESVLAATKPD KESFLTWL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Full length protein
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage
Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation.
Gene References into Functions
  1. FatJ mediates its action via the Hippo pathway mediator Yap1: loss of downstream Hippo components can rescue the defect caused by loss of FatJ. PMID:21521736

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Subcellular Location
Cytoplasm. Nucleus.
Protein Families
YAP1 family
Database Links

UNIGENE: Gga.3093

KEGG: gga:396171

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