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Recombinant Chicken Tyrosine-protein phosphatase non-receptor type 1 (PTPN1)

Recombinant Chicken Tyrosine-protein phosphatase non-receptor type 1 (PTPN1)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

PTPN1

Uniprot NO.

O13016

Alternative Names

PTPN1; PTP1B; Tyrosine-protein phosphatase non-receptor type 1; EC 3.1.3.48; CPTP1; Protein-tyrosine phosphatase 1B; PTP-1B

Species

Gallus gallus (Chicken)

Source

Yeast

Expression Region

1-434

Target Protein Sequence

MEIEKEFHRL DQAASWAAIY QDIRHEASDF PCKVAKHPRN KNRNRYRDVS PFDHSRIKLN QGDNDYINAS LIKMEEAQRS YILTQGPLPN TCGHFWEMVW EQKSRGVVML NRVMEKGSIK CAQYWPRKEE KEMFFEDTNL KLTLISEDIK SYYTVRQLEL ENLTTQETRE ILHFHYTTWP DFGVPESPAS FLNFLFKVRE SGSLNPEYGP VVVHCSAGIG RSGTFCLVDT CLLLMDKRKD PSSVDVKQVL LEMRKYRMGL IQTADQLRFS YLAVIEGAKF IMGDASVQEQ WKELSNEDLD PPPEHTPPPP RPPKRTSEMH NGRMHEHAEF FPKHQVVEEE IRCSVSTAEE TVSDGRVFSS VPLITDSTSQ DTEIRRRTVG ENLHVTAHKE ESKSESVEED DENMMTTWKP FLVNICMFTF LTAGAYLCYR VCFH
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function(From Uniprot)

May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.

Gene References into Functions

Growth cone contact with cellular targets is accompanied by invasion of PTP1B and stable microtubules in the peripheral region aligned with the contact axis PMID:19158394

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Subcellular Location

Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.

Protein Families

Protein-tyrosine phosphatase family, Non-receptor class 1 subfamily

Database Links

UNIGENE: Gga.4404

KEGG: gga:395688

STRING: 9031.ENSGALP00000012986

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